Two Cases of Hypertrophic Cardiomyopathy in the Infants of Diabetic Mother

Hypertrophic cardiomyopathy(HCM) in the infant of diabetic mother is transient, nonfamilial condition with morphologic and functional abnormalities that resemble familial HCM. However, unlike ""true"" HCM, the cardiomyopathy of infants of diabetic mothers is usually innocent and transient, resolving during the first 6 months of life. Cardiorespiratory distress may improve within 2 to 4 weeks. Reported are two cases of infants with hypertrophic cardiomyopathy, attributed to maternal diabetes. These infants developed respiratory distress within a few hours after birth, but needed only supportive care. Echocardiogram showed myocardial hypertrophy regressing over two to four months.