Risk Factors of Non-alcoholic Steatohepatitis in Childhood Obesity / 대한소아소화기영양학회지

PURPOSE: Obesity has recently emerged as a significant health problem in the pediatric population, and the prevalence of non-alcoholic fatty liver disease is increasing in tandem with a significant rise in childhood obesity. Therefore, this study was conducted to clarify the risk factors of non-alcoholic steatohepatitis in obese children. METHODS: We enrolled 84 obese children who visited the pediatric obesity clinic at Yeung-Nam university hospital. The patients were divided into two groups based on their alanine aminotransferase (ALT) level (separated at 40 IU/L), and the mean of ages, total cholesterol levels, HDL-cholesterol levels, LDL-cholesterol levels, triglyceride (TG) levels, as well as the mean obesity index, and body fat percentage of the two groups were then compared. RESULTS: When the mean of ages (10.5+/-1.6 vs. 10.7+/-2.0 years), total cholesterol levels (183.0+/-29.1 vs. 183.7+/-31.3 mg/dL), HDL-cholesterol levels (53.0+/-10.2 vs. 55.7+/-13.0 mg/dL), LDL-cholesterol levels (113.4+/-30.2 vs. 113.0+/-30.0 mg/dL), triglyceride levels (99.4+/-62.9 vs. 114.2+/-47.3 mg/dL), obesity indexes (44.7+/-12.2 vs. 47.9+/-15.1%), and body fat percentages (32.7+/-5.0 vs. 34.0+/-4.8%) of group 1 (ALT or =41 IU/L), no significant differences were observed (p>0.05). However, hypertriglyceridemia (TG> or =110 mg/dL) was more frequent in group 2 than in group 1 (p=0.023). CONCLUSION: TG may be an important risk factor in non-alcoholic steatohepatitis and further study regarding the risk factors in non-alcoholic steatohepatitis is required.

Risk Factors of Non-alcoholic Steatohepatitis in Childhood Obesity / 대한소아소화기영양학회지

PURPOSE: Obesity has recently emerged as a significant health problem in the pediatric population, and the prevalence of non-alcoholic fatty liver disease is increasing in tandem with a significant rise in childhood obesity. Therefore, this study was conducted to clarify the risk factors of non-alcoholic steatohepatitis in obese children. METHODS: We enrolled 84 obese children who visited the pediatric obesity clinic at Yeung-Nam university hospital. The patients were divided into two groups based on their alanine aminotransferase (ALT) level (separated at 40 IU/L), and the mean of ages, total cholesterol levels, HDL-cholesterol levels, LDL-cholesterol levels, triglyceride (TG) levels, as well as the mean obesity index, and body fat percentage of the two groups were then compared. RESULTS: When the mean of ages (10.5+/-1.6 vs. 10.7+/-2.0 years), total cholesterol levels (183.0+/-29.1 vs. 183.7+/-31.3 mg/dL), HDL-cholesterol levels (53.0+/-10.2 vs. 55.7+/-13.0 mg/dL), LDL-cholesterol levels (113.4+/-30.2 vs. 113.0+/-30.0 mg/dL), triglyceride levels (99.4+/-62.9 vs. 114.2+/-47.3 mg/dL), obesity indexes (44.7+/-12.2 vs. 47.9+/-15.1%), and body fat percentages (32.7+/-5.0 vs. 34.0+/-4.8%) of group 1 (ALT or =41 IU/L), no significant differences were observed (p>0.05). However, hypertriglyceridemia (TG> or =110 mg/dL) was more frequent in group 2 than in group 1 (p=0.023). CONCLUSION: TG may be an important risk factor in non-alcoholic steatohepatitis and further study regarding the risk factors in non-alcoholic steatohepatitis is required.

Transient Abdominal Distension in Neonate / 영남의대학술지

Abdominal distension is not an uncommon symptom in the neonate; it is indistinguishable from Hirschsprung disease by symptoms and X-ray findings. In three patients, severe abdominal distension was found at early infancy and improved with conservative treatment without relapse. The findings were different from those of Hirschsprung disease. Immaturity or poor coordination of peristaltic movement is postulated as the cause. With maturation such problems can normalize. However the pathogenesis remains unclear and further investigation is needed to improve our understanding.

A Case of Granulation Tissue of the Tongue in Infant / 영남의대학술지

Tongue tumors of pediatric patients are the most common soft tissue tumor of pediatric oral and maxillofacial tumors. There are many kind of pediatric tongue lesions such as hemangioma, lymphangioma, papilloma, and cyst. Most of these lesions are benign, but malignant tumors of tongue may be occurred. Therefore, malignancy should be ruled out. Sometimes, tongue lesions are present with dyspnea, dysphagia, dysarthria, bleeding, or cosmetic problem. We experienced a case of chronic inflammatory mass on posterior 1/3 of the tongue in 4 month old female patient. Swallowing difficulty and respiratory distress symptom occurred because of tongue mass effect. The tongue mass was confirmed as granulation tissue by microscopic examination. After excision of tongue mass, she had no problem with swallowing and breathing.