RESUMO
Successfully managing an unruptured ectopic pregnancy necessitates prioritizing the preservation of fertility as the primary objective. Medical management is traditionally considered to be more successful at lower �- human chorionic gonadotropin (HCG) values. However, there is emerging evidence that successful treatment can be achieved with modification of dosage regimen in the presence of high ?-HCG value. We reported the successful management of a case of unruptured repeat ectopic pregnancy in a patient with high ?-HCG. Mrs PA is a 25-year-old G4P0+3 with previous right salpingectomy due to ruptured ectopic gestation who presented with an ultrasound diagnosis of unruptured left tubal ectopic gestation at a gestational age of 6 weeks. The pre-treatment quantitative ?-HCG level was 7066 IU/l. She had multiple dose methotrexate therapy which was well tolerated with normalization of ?-HCG levels within 44 days. Hysterosalpingography done six (6) months post-treatment demonstrated patent left fallopian tube. She subsequently had spontaneous conception of an intrauterine pregnancy 16-months post-treatment. The pregnancy was carried to term and culminated in successful delivery at term. Multiple-dose chemotherapy was successful in this patient with high ?-HCG level with no reported adverse effect.
RESUMO
Background: Pathology diagnosis is key to critical decision making in clinical medicine. In clinico-pathologic consults, there may be errors in pathologic diagnoses resulting in delayed or inappropriate treatment, hence impaired quality of care. Seeking a second opinion on a pathology consults is one procedure that enhances quality of healthcare services. In the spate of medical litigations, some doctors are either not aware of the procedure or do not utilize second opinion pathology consults (SOPCs). Methods: This cross sectional study used an online structured questionnaire to assess the awareness of and utilization of SOPCs by clinicians in Nigeria. Information regarding socio-demography, cadre, years in practice, reasons for utilization or non-utilization and modalities for seeking SOPCs were collected. Results: Of the 511 respondents, 75.7% of whom practiced in government-run tertiary hospitals, 33.5% have never utilised SOPC. Surgeons (29.7%) and gynaecologists (12.1%) are the major users of SOPCs; utilization of which is associated with cadre (p= 0.001) and not years of practice (p= 0.199). 24.3% divided specimen between pathologists, 15.5% sent a fresh specimen, 15.2% and 24.1% sent out the same slides and tissue blocks respectively, used for the first diagnosis. 65.8% SOPC requests were not accompanied with the first pathologist’s report. Conclusions: SOPC is an important component of a total quality assurance that helps reduce the overall cost of patient care. Many clinicians are not aware of SOPC procedure, hence the under-utilization. It is our opinion that proper enlightenment of clinicians will bridge this gap in knowledge and enhance better practice.