Photo-onycholysis induced by doxycycline: a new clinical feature

Photo-onycholysis is a rare complication of tetracyclines. Three clinical subtypes are usually reported. In type I, several nails are often involved and the separated portion of the nail is half-moon-shaped with proximal convexity. In type II, only one nail is involved and there is a proximal notch due to the concentration of ultraviolet rays. Type III is medio-ungueal, away from distal end and lateral folds of the nail. We report a new form of photo-onycholysis induced by doxycycline resembling the latter subtype. In fact there is no involvement of the distal or disto-lateral end of the nail but the separation of the nail starts from the proximal fold. As far as we know, such a clinical feature has not been reported before

[Quel est votre diagnostic?: Devant une ulceration du lit de l'ongle de l'index?. [Cell carcinoma of the nail bed]

Squamous Cell Carcinoma of the nail bed is rare, about 150 cases are reported in the literature. We present one case revealed after one year of evolution. It presented as an ulceration associated to an onycholysis. Because of this delayed diagnosis, amputation of the whole finger was needed