Advantages and limits of blood assay of theophylline

Theophylline is very effective medication in asthma, but this treatment is not always manageable, due to a narrow therapeutic range. However, with theophylline plasma levels, one can adapt dosages individually in order to obtain an efficient non-toxic plasma level. The most used assay techniques are reliable and rapidly done but need a relatively expensive instruments, which limits currently their development in Morocco

Clinical trials of drugs. About analysis of African reports

Clinical trials of drugs: about analysis of African reports. Clinical trials are currently well codified: some constraints are absolutly necessary to obtain a reliable information. A trial must be randomized, comparative, and should analyse statistically results. We studied all papers concerning clinical trials, published during five years in different African journals, in order to see if they follow these obligations. Only one paper on 48 studied contained the main cited criteria and eight trials were comparative. To improve the quality of clinical trials and their credibility, it seems necessary, before starting such studies to be well informed about clinical trials codification or, at least, take advice with experienced persons in this field