[Survey and comparative study of retinal vein occlusion risk factors]

39 cases of retinal vein occlusion that sequentially attended to eye clinic in 3 years enrolled in this study. The hypertension, cigarette smoking, mean plasma homocystein and age-range in retinal vein occlusion category were compared with 49 controls. 19 cases had Branch retinal vein occlusion and 20 have Central retinal vein occlusion, 15 of them were female and the remainder [24] was male 17 cases had left eye involvement and one has bilateral involvement. Except 5 cases, most of the patients had at least one of 3 systemic diseases [Hypertension, Diabetes, and hyperlipidemia]. The mean plasma homocystein level in cases was 15, 39 micro mol/l and in controls it was 15.95 which was not statistically significant. [p=0.42]. The mean plasma homocystein level was above the normal in 21 cases [13.0 micro mol/l] and in 28 control subjects. This study showed that retinal vein occlusion is mostly associated with one of the systemic diseases. We could not find also statistically significant relation between homocysteine level and retinal vein occlusion in this study

Hyperhomocysteinaemia: risk of retinal vascular occlusion

To investigate the possible relationship between hyperhomocysteinaemia and retinal vascular occlusion, we measured plasma homocysteine levels in 25 patients with a history of retinal vascular occlusion in the previous 2 years and in a control group of 24. The difference in mean plasma homocysteine levels was not statistically significant. All except 5 of the cases had hypertension, diabetes mellitus or hyperlipidaemia. Most of the patients had branch retinal vein occlusion associated with recent onset of occlusion. Factors such as emotional status and associated systemic disease may play a role in predisposition of retinal vascular occlusion, so more-precise studies are needed to determine the possible risk factors of hyperhomocysteinaemia in retinal vascular occlusion