Tinea corporis, clinical and mycological study in Dakahlia

Our study was carried out in an attempt to classify and identify the causative fungi of tinea corporis as well as the incidence of the disease in our locality Trichophyton rubrum was the commonest isolated dermatophyte [35.75%]. Trichophyton violaceum comes next in frequency [16.58%], followed by trichophyton metagrophyte and Epidermophyton floccosum [7.77%], Trichophyton schoenleinii [4.66%] while trichophyton tonsurans [0.25%], trichophyton verrucosum [1.56%] and Microsporum canis [0.52%] were at the lowest end of the list, Candida were isolated from 24.87% of positive cases

Genetic-environmental interaction in psoriasis

The inheritance of psoriasis was studied by analyzing data from 60 families of probands with psoriasis. 10 families were multiplex, and the other 50 were simplex. A significant higher frequency of the disease was found among relatives of probands than among general population, the frequency diminishing as the degree of relationship between relatives and probands descended. Collected data from the pedigrees of the families of probands did not conform to any simple mode of inheritance, and segregation analysis revealed frequencies of psoriasis among siblings of probands which are lower than expected for single gene defects. The results shown by the curve of liability of the relatives, the frequency in first degree relatives and the relative frequency in sibs points to a multifactorial inheritance. The heritability of liability for posriasis, which measures the relative contribution of genetic factors in etiology, was found to be 76.4%