[ sarcoidosis]

Sarcoidosis is a multisystemic granulomatosis seen mainly in the young adult. This is a retrospective study which evaluated 35 cases of sarcoidosis confirmed histologically, during periods from 1985 to 1999. In this study, 88.57% of patients were female with a mean age of 47.5 years old. The main complaint was often a peripheral node lesion followed by an ocular lesion. This clinical study had a very polymorphic presentation. The endothoracic lesions were largely predominant [94.28%], followed by extra thoracic lesions such as cutaneous lesions [big nodules and erythema nodosum], ocular lesions [25.7%], represented by anterior uveitis [4 cases], posterior uveitis [2 cases] and one case of panuveitis. Lymphatic node lesions were present in 63% of cases. The articular involvement was mainly made of inflammatory arthralgia. The bone lesions seen in 5 cases were made of sarcoid dactylitis confirmed histologically in 3 cases. We observed one case of sarcoidosis associated to spondylarthropathy. Prednisone was indicated in 27 patients at a dose of 0.5 to 1mg/kg/day, leading to a good recovery in 58.33 of cases. The mean follow-up was 20 months. Sarcoidosis in Morocco seems to be rare. The association of sarcoidosis and spondylarthropathy was rarely described. Posterior uveitis was present in this series

[Sacroiliac involvement drug rheumatoid arthritis]

The objective of the study is to illustrate the incidence of sacroiliac involvement during rheumatoid arthritis, among 1000 cases seen in a period of 22 years. All patients fulfilled the criteria of American college of Rheumatology [ACR 87]. Were included only those with sacroiliitis diagnosed by X-Ray and a positive rheumatoid serology. 7 cases of radiologic sacroileitis were found [0.7%]; sex-ratio was 0.4; mean age was 42.85 years old; the age at onset was about 5.42 years. All patient had hand and wrist involvement with respect to distal interphalange joints. Deformities were seen in 6 cases and the majority were classified stage II clinically and stage III radiologically [Stein Brocker classification]. We noted that 2 cases of coxitis were associated to the sacroileitis and also 2 cases of subcutaneous nodules. Sedimentation rate was increased around 78 mm. Sacroileitis was classified stage III in 2 cases, one patient presented the diagnosis of spondylarthropathy associated to nodular, destructive and erosive rheumatoid arthritis; the diagnosis of spondylarthropathy was retained on AMOR criteria [7 points] and European Group [ESSG] criteria. The treatment was based on salazopyrine. Sacroiliac involvement during rheumatoid arthritis is not rare and should be explored when suggestive clinical signs are present