Electron microscopic study on the pancrease of albino rat after bilateral vagotomy

Thirty adult male albino rats were included in this study and divided into six equal groups. Bilateral vagotomy was done in four groups, while the other two groups were used as control animals. Generalized swelling of mitochondria of acinar, insular and ductular cells as well as of the nerve terminals appeared by the third day after operation. These changes were more apparent by the 7th, 15th and 30th days with vascular congestion, hemorrhage and cellular infiltration. The early changes were first within the limits of the physiological parameters and destructive process soon occurred