Research advances in prognostic factors for patients with esophagogastric variceal bleeding / 临床肝胆病杂志

Esophagogastric variceal bleeding is one of the most common complications of liver cirrhosis and is also one of the most critical diseases in the department of gastroenterology, with the features of acute onset and high rebleeding and mortality rates. Strengthening the understanding of related prognostic factors has great clinical significance in reducing early rebleeding rate and mortality rate. There are many factors associated with rebleeding and death in patients with esophagogastric variceal bleeding. Risk factors include advanced age, sex, Child-Turcotte-Pugh class C, low platelet count, high leukocyte count, bleeding history, portal broadening, widening of the portal vein, a positive red-color sign under an endoscope, severe varices, and infection, while the percentage of lymphocytes, serum sodium, and the use of non-selective β-blockers and antibiotics are protective factors. By analyzing these prognostic factors, we can learn more about their mechanisms and risk degree. At present, related research mainly focuses on the exploration of better individual treatment regimens and nursing strategies based on the risk assessment models established using these risk factors to reduce the risk of rebleeding and death.

Impacts of different therapies on medical and physical health of breast cancer patients / 现代临床护理

Objective To investigate the impacts of different therapies on medical and physical health of breast cancer patients and put forward the measures for health education. Methods The MOS 36 items short form health survey (SF-36) and a self-designed questionnaire on general data were designed to investigate 93 breast cancer patients with different therapies. All of them had undergone surgery and were divided into two groups as in the following: 21 receiving only surgery were set as only surgery group, 51 receiving surgery plus chemotherapy as another group, 11 of them receiving surgery plus radiotherapy as another group and 10 receiving surgery plus chemotherapy and radiotherapy as the last group. Results There were significant differences between all the groups in terms of the score on physical health ( P<0 . 05 ) and so it was with the only surgery group and the surgery plus chemotherapy group (P<0.05); the surgery plus chemotherapy group and the surgery plus chemotherapy and radiotherapy group (P<0.05). There were significant differences among all the groups in terms of the score of mental health (P<0.05) and so it was with the comparison among the surgery group and surgery plus chemotherapy and radiotherapy group (P<0.05). Conclusions The patients who have surgery plus chemotherapy and radiotherapy are in poor condition physically and mentally. Health education should focus on improving the general and physical health. So we should understand the effect of different therapies on patients physically and mentally. In this way, we can individualize the health education and help the patients with breast cancer to live in a better mental and physical condition.