[ effect of acute L-carnitine supplementation on the blood lactate, glucose, VO[2max] and power in trained men: a brief report]

Probably L-Carnitine can induce increasing of Pyruvate dehydrogenase activity, decreasing of lactic acid production and performance improvements due to the reinforcement of long chain fatty acid oxidation and stabilize of Coenzyme A [CoASH] to free Coenzyme A [COA]. Based on this, the aim of this study was to investigate the effect of acute L-Carnitine supplementation on blood lactate, glucose, VO[2max] and anaerobic power in trained men. Sixteen trained men [aged 19-23] volunteers from University of Guilan, faculty of Physical Education and Sport Sciences participated as subjects in this investigation. Subjects divided to aerobic [A] and anaerobic [An] group randomly. In a double blind design, subjects participated in two separated tests by one week. Subjects ingested 3 grams of L-Carnitine supplementation or placebo [maltodextrin] 90 minute before aerobic and anaerobic exercise. For aerobic activity used shuttle run 20 meter and for anaerobic activity used RAST test. Blood samples were collected 5 minute prior at rest and 4 minute post tests. Participants were asked in the morning to obtain fasting blood samples and perform tests. A t-test was used to detect differences between supplementation and placebo groups in each exercise. L-Carnitine group [[A] 141.25 +/- 20.62 and [An] 145.38 +/- 55.47] significantly had lower lactate concentration than placebo [[A] 151.00 +/- 20.85 and [An] 152.50 +/- 28.59] after tests [P

[ study of two months walking exercise on serum lipoprotein and body mass index in obese girls]

Obesity, a public health problem is growing in prevalence over the recent decade. One morbidity associated with obesity is cardiovascular disease [CVD] which is invariably related to dyslipidaemia. The purpose of the present study is to examine the effect of walking exercise in order to reduce the risk of [CVD] in sedentary obese girls. Twenty untrained obese [BMI>30] girls with age 22.00 +/- 1.50 years volunteer took place in this research and then they were randomly divided in two groups [Control: n=10 Experimental: n=10]. At first and after 2 months HDL-c, LDL-c and BMI were assessed. Then the experimental group started to do exercise programme. The data by unpaired- t-test at the level of p<0.05 were analyzed. The study finding showed that reduced BMI [p=0.001], LDL-c [p=0.006]significantly decreased but HDL-c [p=0.004] significantly increased in exercise group. This study demonstrated that a programme of regular physical activity such as walking exercise significantly can[S8] change the lipoprotein's metabolism in body and reduce the risk of [CVD] in obese girls