Effect of mobile phone usage time on total antioxidant capacity of saliva and salivary immunoglobulin A

Nowadays mobile phone is very popular, causing concern about the effect it has on people's health. Parotid salivary glands are in close contact to cell phone while talking with the phone and the possibility of being affected by them. Limited studies have evaluated the effect of cell phone use on the secretions of these glands; so this study was designed to investigate the effects of duration of mobile phone use on the total antioxidant capacity of saliva. Unstimulated saliva from 105 volunteers without oral lesions collected. The volunteers based on daily usage of mobile phones were divided into three groups then total antioxidant capacity of saliva was measured by Ferric Reducing Ability of Plasma [FRAP] method. Data were analyzed by SPSS software version 19. ANOVA was used to compare 3 groups and post-hoc Tukey test to compare between two groups. Average total antioxidant capacities of saliva in 3 groups were 657.91 micro mol/lit, 726.77 micro m/lit and 560.17 micro mol/lit, respectively. The two groups had statistically significant different [P=0.039]. Over an hour talking with a cell phone decreases total antioxidant capacity of saliva in comparison with talking less than twenty minutes

Comparison of effectiveness of the bioadhesive pastes containing licorice 5% and topical corticosteroid for the treatment of oral Lichen Planus: a pilot study

Lichen planus is a chronic inflammatory mucocutaneous disease with immune system's origin. There is no definite cure for that and present treatment methods are symptomatic. According the effects of topical medications and anti-inflammatory properties of licorice, this study is designed for comparison the effectiveness of the adhesives containing licorice with topical steroid on treatment of oral lichen planus. In this double-blind clinical trial, 40 patients randomly divided into two groups: licorice and topical corticosteroid therapy and were followed up for 12 weeks, we asked patients used the drugs four times in a day and after applying drugs avoid of eating, drinking and smoking for an hour. Data were analyzed by SPSS-19, using the independent samples t-test and Mann-Whitney U tests. In this study the use of topical licorice as topical corticosteroids were effective in reducing pain, but the improvement of clinical signs was not effective as corticosteroids. The severities of lesion according Thongprasom classification were 1.2 +/- 1.03 in corticosteroid group and 2.6 +/- 0.9 in licorice group. There was a statistical significant difference between groups [p=0.006]. Based on the findings of this study topical licorice 5% is not a good alternative for topical corticosteroids in the treatment of lichen planus

Evaluation of hematologic status in patients with recurrent aphthous stomatitis in an Iranian population

The aim of the present study was to compare hematologic problems in patients with recurrent aphthous stomatitis, with a control group. In this cross sectional study, 30 subjects with recurrent aphthous stomatitis and 30 healthy individuals were included as the case and control groups, respectively. After diagnosis was established a 10 ml sample of the subjects' blood was used to determine serum levels of iron, ferritin, vitamin B12, folic acid and zinc in each subject. Independent t-test was used to analyze data. The average serum iron, serum ferritin, vitamin B12, folic acid and serum zinc levels in the case and control groups were assessment, demonstrating no statistically significant differences between the two groups [p>0.05]. According to the results of the present study, hematologic deficiencies cannot play a role in etiology of aphthous stomatitis

evaluation of psychological factor and salivary cortisol and IgA levels in patients with oral Lichen Planus

Oral lichen planus [OLP] is a chronic immunological disorder with unknown etiology. The aim of this study was to determine psychological factors and salivary cortisol, IgA level in patients with oral lichen planus. In this experimental study 20 patients with OLP and healthy person were admitted to this study. Saliva samples were collected between 9-10 Am. saliva cortisol, IgA level was detected by ELIZA method. In this study, patients with anxiety and depression were measured using the SCL-90 questionnaire. Data analyzed by t-test. The mean salivary cortisol level in patients with OLP was 3.2 +/- 1.9 ng/mL and the mean saliva cortisol level in healthy person was 3.5 +/- 1.9 ng/mL. Significant difference was observed in the salivary cortisol levels in the 2 study groups [p=0.04]. The mean salivary IgA level in patients with OLP was 0.69 +/- 0.29 ng/mL and the mean saliva IgA level in healthy person was 0.9 +/- 0.43 ng/mL but no significant difference was observed in the salivary cortisol levels in the 2 study groups. Results showed that anxiety levels in patients with oral lichen planus were slightly higher than controls but there was no significant difference between healthy subjects. Finding revealed the mean salivary cortisol level in patient with OLP less than healthy persons. Significant difference was observed in the salivary cortisol levels in the 2 study groups. Based on the t-student test, no significant difference was observed in the salivary IgA levels in the 2 study groups. Anxiety levels in patients with oral lichen planus were slightly higher than controls

Evaluation of chemoprevention effect of systemic celecoxib on induction of tongue neoplasms in rat

Cyclo-oxygenase-2 [COX-2] specific inhibitors were examined for predication or treatment of different tumors and it is indicated that COX-2 specific inhibitors play an important regulatory role in apoptosis of tumoral tissues. Therefore, the present study was designed in order to examine the preventive effects of a COX-2 specific inhibitor called. celecoxib on 4-nitroquinoline 1-oxide [4NQO]-induced squamous cell carcinoma on rat. In this experimental study, 30 Sprague Dawley rats [with the age of 3- 3.5 months] were selected and divided into three groups. In order to induce lingual carcinoma, 4NQO powder was prepared 3 times a week for each cage. In this study, celecoxib power was mixed with a basic food [basal diet] in order to examine the systematic effect. Tongue samples were sent to laboratory for immunohistochemical [IHC] staining and histological examination. Based on morphological criteria and the ratio of apoptosis to cell proliferation, the prevalence of tongue precancerous lesions was reduced significantly by celecoxib. Celecoxib systematic has inhibitory effects on the 4-nitroquinoline 1-oxide [4NQO]-induced squamous cell carcinoma of tongue. The effect of celecoxib is probably via suppression of cell proliferation and induction of apoptosis

Comparison the antifungal effect of licorice and nystatin, invitro study

Candida Albicance is one of the most common oral opportunistic infection. Antifungal drugs have several side effects as well as bad taste. Licorice is one of the oldest drugs in Iranian traditional medicine. It has antibacterial and antiviral effects; however, there are a few studies about its antifungal. Therefore, this study was designed for in vitro evaluation of the antifungal effect of licorice. Candida Albiance [TIMM 2640] was cultured. After licorice extract was prepared, its antifungal effect was compared with that of nystatin using agar diffusion method. Diameter of inhabitation zone was 32.60 +/- 0.84 mm in nystatin group and almost zero in licorice groups. There was statistically significant difference between nystatine and licorice extract [P=0.002]. Based on the result of this in vitro study, licorice extract did not show any antifungal effect

comparison between video tape and live demonstration methods for teaching of fissure sealant placement procedures for dental students of Zahedan university of Medical sciences in 2010-2011

Teaching of clinical skills is one of the most important aspects in training medical students. The aim of this study was to compare the effectiveness of videotaped and live demonstrations for applying fissure sealant on permanent molar teeth at Zahedan University of Medical Sciences [2010-2011]. Thirty 8th-semester dental students were randomly assigned in two groups [n = 15]. In group 1, fissure sealant placement was taught using live demonstration; while, in group 2, education was performed by videotaped demonstration. Then, each student applied fissure sealant on the patient's permanent molar tooth. The procedure of fissure sealant placement was assessed and scored by a pedodontist. The students were subsequently asked to rate how helpful the videotape or live demonstration had been. The data were analyzed using T-test and Chi-square test. The mean students' scores for videotaped and live demonstration were 16.5 and 16.53, respectively. There was no significant difference between the teaching methods according to students' scores [P>0.05]. 33% of students rated videotaped demonstration as [good] for its helpfulness and 66% as [very good]. However, live demonstration was rated as [good] and [very good] by 66% and 33% of students, respectively. There was no significant difference between two groups [P>0.05]. Both teaching methods were equally effective. Therefore, videotaped demonstration can be used in combination with live demonstration or as an alternative for it

Evaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: a double-blind randomized clinical trial

Oral mucositis is a serious complication of chemotherapy that results in painful debilitating inflammation, necessitating the administration of analgesics. There is no cure for mucositis. Some studies have evaluated the effect of zinc sulfate on mucositis. The present study aims to evaluate the effect of oral zinc sulfate on prevention of mucositis, xerostomia, and pain induced by chemotherapy. This double-blind, randomized controlled trial was carried out on 50 adult patients who underwent chemotherapy during 2008-2009. Patients were divided in two groups. Patients in the intervention group were administered three, 220 mg zinc sulfate capsules daily until the end of their chemotherapy treatment. Patients in the placebo group received three placebo capsules daily, which were similar in shape, taste, and color to the zinc sulfate capsules. Data were analyzed by SPSS version 17 software, using the independent samples t-test, Mann-Whitney U and Friedman tests. The incidence of grade 3 mucositis was lower in the zinc sulfate group. In the first follow up, grade 3 mucositis was detected in 10% of patients. In the placebo group, grade 3 mucositis was seen in 46.6% of patients. By the fourth follow up, grade 3 mucositis was detected in 3.33% of patients in the intervention group and in 20% of patient in the placebo group. At the end of the study there was no grade 3 mucositis detected in the zinc sulfate group, whereas there were 3.57% of patients in the placebo group with grade 3 mucositis. The results also showed that zinc sulfate decreased the effects of xerostomia and pain in patients under chemotherapy treatment. It can be concluded that zinc sulfate might decrease the intensity of mucositis