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Reviews in Clinical Medicine [RCM]. 2014; 1 (4): 194-199
em Inglês | IMEMR | ID: emr-180790

RESUMO

Heart failure [HF] is a serious and growing public health concern, whichhas many causes. Pregnancy is a critical condition with significanthemodynamic and immunologic changes. Peripartum cardiomyopathy[PPCM] is a disease of unknown cause in which left ventricular [LV]dysfunction occurs during the last trimester of pregnancy or the earlypuerperium. PPCM is known to be the most common cardiovascularcause of severe complications in pregnancy. Risk factors for peripartumcardiomyopathy include advanced maternal age, twin pregnancy,smoking, pregnancy-related hypertension and preeclampsia, multiparity,African descent, and long-term tocolysis. Oxidative stress and someinflammatory markers have been diagnosed in PPCM pathophysiology.Recent observations have suggested that bromocriptine might favorrecovery of LV systolic function in patients with PPCM. Patientsdeveloped peripartumcardiomiopathy treated with bromocriptine showedsignificantly improved LV ejection fraction and heart failure symptoms.This article tries to have a short review on this clinical scenario

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