Evaluation of some biochemical changes related to liver among workers manufacturing pesticides

This study was done on 250 non-bilharzial non-alcoholic male workers in a pesticide manufacturing plant, exposed to different types of pesticides and other 50 non-exposed controls. Each worker was subjected to full clinical history and examination as well as biochemical and hematological analysis. Results indicated that exposure to pesticides has not results in enlargements of the liver and/or spleen. It leads to significant inhibition of ChES activity. Other biochemical changes were in the form of hypoglycemia, hypocholesteremia, increase in triglycerides and increase in serum GGT activity