RESUMO
Histological lesions of viral hepatitis, viral colitis and viral nephritis-cystitis, characterized by presence of intracytoplasmic inclusion bodies in involved tissues, were seen in goats that died of acute unrecognized diseases. The viral inclusion bodies stained positively by special staining for viral nucleic acid. Viral hepatitis was diagnosed in an adult goat which experienced a fulminating acute disease. Post-mortem examination showed that the liver was swollen and dark in color. Histopathological examination revealed severe congestion, fatty change and necrosis of the liver cells as well as presence of eosinophilic intracytoplasmic inclusion bodies in the hepatocytes. Viral colitis was diagnosed in 3 kids that died of severe haemorrhagic diarrhoea. The disease occurred in a small farm containing about 75 kids, 22 of which died of clinical disease. None of the adult animals showed clinical signs. The lesions were confined to the colon which was haemorrhagic and full of clotted blood. Histopathological examination showed haemorrhagic ulcerative colitis and presence of acidophilic intracytoplasmic inclusion bodies in the mucosal epithelium. Bacteriological examination showed presence of enterotoxogenic Echerichia coli. Viral nephritis-cystitis was diagnosed in a male kid of about 4 months old. The animal developed acute disease with bloody urine and died within one day of appearance of clinical signs. The lesions were confined to the urinary system and that both renal pelvis and urinary bladder were full of clotted blood. Extensive haemorrhage was present in the renal cortex and medulla. Histopathology revealed necrosis of both renal tubules and glomeruli, haemorrhagic cystitis and presence of intracytoplasmic inclusion bodies in the transitional epithelium of the urinary bladder and glomerular lining. Bacteriological examination was negative for leptospirosis