Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Adicionar filtros








Intervalo de ano
1.
Egyptian Journal of Medical Laboratory Sciences. 2007; 16 (2): 89-97
em Inglês | IMEMR | ID: emr-82213

RESUMO

Leukemia is the most common malignancy of childhood [33%] where Acute Lymphoblastic Leukemia [ALL] is the most common type in children. is to study the effect of ALL on complete blood count [CBC] and on some important biochemical parameters as total protein, albomin, globulin, uric acid, lactate dehydrogenase [LDH], erythrocyte superoxide dismutase [eryth. SOD] and erythrocyte glucose-6 -phosphate dehydrogenase[eryth. G-6-PD]. Also to measure total DNA and RNA content in all the samples. Moreover to carry out a comparative study of these parameters before and after treatment in contrast to control group. This study included forty newly diagnosed children with [ALL] in National Cancer Institute [NCI], Cairo University. Blood samples on admission [Gr. IIA] and after 4 weeks of chemotherapeutic treatment [Gr. IIB] were analyzed. Four cases died 2 weeks from diagnosis, one case discontinued, and one case failed to remission induction. CBC revealed a significant remarkable decrease in the hemoglobin content, RBCs and platelet count in [Gr. IIA] and these parameters were improved in [Gr. IIB]. A significantly marked elevation in WBCs and blast cells were recorded in [Gr. IIA]. On remission they returned to their normal level in [Gr. IIB]. Total DNA and RNA contents revealed a significant remarkable elevation in [Gr. IIA], while after 4 weeks of treatment they returned to normal level [Gr. IIB]. G-6-PDH showed significant increase in [Gr. IIA] while SOD activity showed high significant decline in [Gr. IIA]. After treatment both G- 6-PD and SOD showed significant improvement [Gr. IIB]. One month of chemotherapeutic treatment is not enough to achieve complete hematological remission for Egyptian [ALL] children in contrast to European reports. Biochemical parameters returned to their normal level, yet G-6-PD and SOD activities were improved largely. Also measurement of G-6-PD and SOD activities and DNA and RNA contents are useful markers to follow up ALL children after chemotherapeutic treatment


Assuntos
Humanos , Masculino , Feminino , Criança , Biomarcadores , Glucosefosfato Desidrogenase , Superóxido Dismutase , Contagem de Plaquetas , Seguimentos
2.
New Egyptian Journal of Medicine [The]. 1989; 3 (5): 1737-40
em Inglês | IMEMR | ID: emr-14459

RESUMO

This study was carried out on 20 normal control, twenty oligospermic subjects [sperm count < 20x 10[6]]; and ten azospermic individuals. Serum triiodothyronine and tetraiodothyronine; thyroxine [T3 and T4] were estimated as parameters for the thyroid function.Motility and sperm count were carried out on semen specimens. Serum total proteins, albumin, the albumin/globulin ratio [A/G] ratio and calcium were also determined. This study pointed to a relationship between infertility and hyperthyrodisim in the oligospermic groups. Results are tabled and discussed


Assuntos
Glândula Tireoide/fisiologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA