Evaluation of new technique of mesh fixation in laparoscopic inguinal hernia repair

Background: Hernia is a common problem of the modern world with an incidence ranging from 5 to 7%. Of all groin hernias, around 75% are inguinal hernias. Recently with the advancement in laparoscopy, endoscopic repairs seem to offer better quality of life, decreasing hospital stay and early return to work. Aim of the work was to evaluate a new technique for mesh fixation by Zein method of suturing and compare it with stapled mesh fixation in laparoscopic inguinal hernia repair transabdominal preperitoneal approach.Methods: The study is a randomized, prospective single group study. The study was conducted after the approval of the ethical committee of the surgical department, Menoufia University. It was conducted in Menoufia University Hospital on 50 patients with inguinal hernia who were operated upon between September 2018 and September 2019 with a minimal follow-up of 6 months.Results: Age of studied patients ranged from 27 to 55 years with mean 42.82±7.90 age/years. Regarding sex of studied patients, more than half (74%) of studied patients were males and (26%) were females. Regarding comparsion between high and low overall cost burden on the patient, it was interestingly found that high cost is associated with presence of complication like hematoma, prolonged stay in the hospital and prolonged use of antibiotics.Conclusions: Both the use of sutures and fixation of mesh by absorbable tacks approaches are similarly effective in terms of operative time, the incidence of recurrence, complications, and chronic pain coinciding with all the available literature.

Coagulation profile tests as a predictor for adult trauma patients’ mortality

Background: Coagulopathy is commonly observed in poly-traumatized patients and is a known contributor to trauma mortality. Although, the incidence of coagulopathy is strongly associated with the severity of the injury, coagulopathy itself exerts an independent factor on mortality.Methods: This is a prospective, observational study on 100 trauma patients. All patients were evaluated using the modified shock index (MSI). Coagulation profile tests including platelet count, prothrombin time (PT), partial thromboplastin time (PTT), D-dimer and fibrinogen/fibrin degradation products (FDPs) were performed for all patients on admission and at 12 hours intervals. Statistically, a logistic regression analysis was performed of coagulation profile tests to determine the incidence of trauma induced coagulopathy (TIC) and its impact on 24 hours mortality. Correlation between clinical and laboratory status was done.Results: There was a statistically significant difference between the dead and the survived patients in the coagulation profile tests and MSI. The best cut-off point of each parameter of coagulation profile tests (PLT count, PT, PTT, d-dimer, FDPs) and MSI was calculated using receiver operating characteristic curve and were <173 × 109/l, >18.7 s, >31 s, >5 mg/l, > 321.5 mg/l and 1.6 respectively. Trauma induced coagulopathy in our study was defined by more than 2 of the following: PLT <173 × 109/l, PT >18.7 s, activated partial thromboplastin time (APTT) >31 s, D-dimer >5 mg/l and FDPs>321.5 mg/l with a p value 0.001 and associated with increased mortality.Conclusions: The incidence of trauma induced coagulopathy early after trauma is high and its severity is related to the injury itself. It is independent predictor of mortality. TIC was developed with presence of more than 2 of the coagulopathy parameters.

Incidence of jaundice in mature, premature, and small for date neonates

The aim of this study was to investigate the incidence of neonatal jaundice in Egyptian mature, premature and small for date neonates. The study was conducted on neonates administered to NICUs in Al-Galaa and Sayed Galal hospitals in the period from January to June 2007. The total number of admitted neonates was 1048, out of them 257 developed neonatal jaundice, 150 of them were chosen and divided to three equal groups i.e. full-term group, premature group and small for date group. These neonates were subjected to prenatal history, full clinical examination and full laboratory investigations. The study showed that the incidence of neonatal jaundice was 24.5%, the incidence in low birth weight [preterm and small for date] neonates was higher than in full term neonates and that the date of appearance was earlier in preterm than in full term and small for date. Total serum bilirubin was higher in preterm than in full-term and small for date. The study showed that the incidence of Caesarian section was higher in preterm neonates than in full-term and small for date neonates and that total serum bilirubin was higher in small for date neonates delivered by Caesarian section than those delivered by normal or assisted delivery

Effect of ozone on some blood coagulation patterns in male albino rats

In this study forty adult male albino rats were used to investigate the effect of ozone on some coagulation patterns. Rats were divided into four equal groups, i.e. control group, immobilization stress group, immobilization plus small dose ozone group and immobilization plus large dose ozone group. In each group prothrombin time [PT], partial prothrombin time [PPT], platelet count, malonyldialdehyde, and catalase enzymes were measured. The results showed that immobilization stress led to significant increase in prothrombin time, partial prothrombin time and malonyldialdehyde with significant decrease in platelet count and catalase enzyme as compared to control group. Ozone in small dose led to significant decrease in prothrombin time, partial prothrombin time and malonyldialdehyde with significant increase in platelet count and catalase enzyme as compared to immobilization stress group. Ozone in large dose led to significant decrease in prothrombin time, partial prothrombin time and malonyldialdehyde with significant increase in platelet count and catalase enzyme as compared to immobilization stress group. The results of this study showed that immobilization stress had hypocoagulability effects and that ozone in large and small doses had improved these immobilization-induced hypocoagulability changes

Effects of body weight on some house works efficacy and some physiological parameters of females

In this work the effect of excess body weight on house works and some physiological parameters were conducted on twelve females' university students. The students were divided into a control [normal weight] group and experimental [overweight] group. The weakly cleaning of the living room was chosen as house work. A room was prepared as a living room with some furniture like tables, chairs, a sofa and cupboard in addition to a carpet on the ground and curtains on the walls. Observation of complexion, tremors, behavior reflecting boredom , level and time of performance as well as any complaint as tiredness, back pain, leg pain. Some physiological parameters as pulse, blood pressure, respiratory rate forced respiratory capacity and expiratory time were measured. The results showed that overweight has passive effect on time and level of performance; also it affects the circulatory functions more than the respiratory functions. So house works are not considered as hard work and not sufficient to reduce body weight in overweight women. Also house works can be tolerated and there is no need to restrict activity to guard against respiratory distress

Effect of repeated immobilization on musculoskeletal system and parathyroid hormone in male albino rats

In this study, 40 adult male albino rats were used to investigate the effect of repeated immobilization stress on the musculoskeletal system and parathyroid hormone. The rats were divided into two equal groups [control and experimental]. The rats of the control group were kept in the housing cages, while those of the experimental group were put singly in cages 10 x 5 x 5 cm for six hours daily, then returned to the housing cages. This procedure was continued for 15 days. At the end of the experiment, blood was taken to estimate serum calcium, phosphorus, alkaline phosphatase and parathyroid hormone. Specimens from skeletal muscles, long bones and joints were taken for a histological examination

Age-related response to noise stress on gastric secretion and ulceration in male albino rats

The effects of noise on gastric secretion and ulceration in male albino rats were investigated. Forty-eight rats were used and divided into three main groups i.e. young, adult and senile. Each group was subdivided into control and experimental subgroups. The experimental animals were exposed to noise stress [100 dB] one hour daily for four weeks. The results showed that noise decreased the volume and total acid output in all animal groups and increased the titratable acidity in young group. Noise increased the ulcer index in adult and senile groups and led to vascular congestion, inflammatory cell infiltration, glandular deformity, mucosal atrophy and musculosa hypertrophy in the stomach of all groups

Effect of unsatisfied sexual excitation on reproductive system in male albino rats

Sixty adult albino rats [20 males and 40 females] were used to study the effect of sexual excitation on the male genital system. Rats were divided into two equal groups i.e. control and experimental. Rats were exposed to continuous sexual excitation for one month. Hormonal studies showed imbalance in the pituitary gonadotrophic and corticotrophic hormones as well as testosterone and cortisol. Histological studies showed severe affection of the secretory sex organs [testes, seminal vesicles and prostate] with no significant affection of the penis and vas deference

Acoustic rhinometric study of the nasal cycle in tracheostomized and laryngectomized patients

This study was performed on 13 postoperative tracheostomized cases, 11 postoperative laryngectomized patients and 10 control subjects. Acoustic rhinometry was used to determine minimum nasal cross- sectional area and nasal cavity volume as indices of nasal patency. Testing was repeated at an interval of 30 minutes over a period of 3-8 hours. The results demonstrated that there was normal cyclical fluctuations in nasal patency after airflow deprivation by tracheostomy and laryngectomy albeit of lower amplitude than normal. Different patterns were recorded with an irregular pattern being the most frequent pointing to crucial role of peripheral receptors on central controlling mechanism. The cycles tended towards normality sometimes after surgery. This interval was longer after laryngectomy compared with only tracheostomy indicating that even minimal airflow through the nose may be enough to stimulate nasal receptors and reestablish a trend towards normality