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Background: Introduction: Intrahepatic cholestasis of pregnancy (ICP), is the most common liver disease specific to pregnancy. Previous studies of fetal effects have suggested that ICP is associated with a higher rate of adverse neonatal outcomes including preterm birth, neonatal respiratory distress syndrome (RDS), meconium-stained amniotic fluid, neonatal intensive care unit admission, and stillbirth. Material & Methods: This was a 4 year retrospective observational study including 43,344 female who delivered in our hospital out of which 1126 cases of ICP were identified, who were compared with 1136 age and parity matched controls. Results: : Previous history and family history of ICP was significant in the ICP group. Gestational diabetes and preterm labour were more frequent in the ICP group. Mean birth weight was lower in the ICP group, rate of small for gestational age foetuses was not significantly different. Cesearean section and post-partum haemorrhage was more frequent in the ICP group. Adverse neonatal outcomes i.e. respiratory distress syndrome (RDS) and need for NICU admission were more in the ICP group. Conclusion: ICP is associated with increased rate of preterm delivery, post-partum hemorrhage and increased neonatal morbidity. Management of patients with ICP should be individualized based on the severity of symptoms and associated medical complications.
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Background: To study the menstrual abnormalities among adolescent females attending a gynaecolocial outpatient department (OPD) in a tertiary care hospital. Material & Methods: It was a cross sectional study which was carried at outpatient department (OPD) of obstetrics and gynaecology, Government medical college Srinagar over a period of 6 months. A total of 90 adolescent females in the age group 10-19 years were included in the study. Along with the demographic profile, menstrual abnormalities were evaluated with the help of self-structured questionnaire. Results: The mean age of the study population was 15.6 ± 2.8 years. Majority of the adolescent females were in the age group of 16-19 years (44.4%), literate with formal education above 10th class (37.8%) and from rural background (56.7%).Dysmenorrhea was the most common menstrual morbidity in 64.4% of adolescent females followed by menorrhagia (26.7%). Pain abdomen was the most common premenstrual symptom encountered by 62.2% of females. Conclusion: Menstrual abnormalities are common in the adolescent females with dysmenorrhea being the commonest.
RESUMO
Background:Migraine is a highly prevalent and disabling neurological disorder associated with a wide range of psychiatric comorbidities.The aimof the studywas tostudy the psychiatric comorbidities in patients with migraine.Methods:The study population comprised all the out patients who fulfilled the diagnostic criteria of migraine attending a tertiary care psychiatry hospital over a period of 6 months.A total of 90 cases of migraine seen over a period of 6 months were analysed to know the demographic characteristics, clinical pattern and psychiatric comorbidity.Results:Maximum patients were between 21-40 years of age group (41.1%), females (83.3%), married (74.4%) and housewives (52.2%). 64.5% of study population was literate with a formal education above 10thstandard. Migraine without aura was commonest sub-type (65.6%).Noise (75.6%) and sunlight (65.6%) was the most common precipitating factors. Anxiety disorders were the most common comorbid psychiatric disorders (40%), followed by major depressive disorder (24.4%). In 24.6% cases, no psychiatric comorbidity was present.Conclusions:Migraine is comorbid with several psychiatric disorders, including anxiety and depressive disorders. When migraine and a comorbid psychiatric disorder are present, it is important to take both disorders into account in formulating a treatment plan.