Effectiveness of health education provided by general practice team in standardizing insulin administration and blood glucose control for diabetic patients / 中华全科医师杂志

The general practice team of the Affiliated Hospital of Hangzhou Normal University and its medical consortium conducted health education for 73 diabetic patients from January to December 2019. The education was dealing with the knowledge and techniques of standardizing insulin administration, including the manipulations, rotation of injection sites and replacement of injection needles, etc. The questionnaire surveys on the knowledge of diabetic management and insulin administration were conducted before and after education. After education the number of patients who knew the injection site and skin disinfection increased from 68 and 69 to 73 and 73, respectively ( P>0.05); the number of patients who knew the injection depth and length of the needle used increased from 33 and 24 to 73 and 73, respectively ( P<0.05); the number of patients who knew pinching the skin, the angle of needle insertion increased from 30 and 44 to 73 and 73 ( P<0.05). After education the number of patients with pinch time>10 sec increased from 0 to 68 cases ( P<0.05); with needle stay>10 sec increased from 0 to 71 ( P<0.05); with rotation in the same area increased from 58 to 73 ( P<0.05); with repeated needle use decreased from 73 to 70 ( P>0.05). After education the blood glucose control of diabetic patients was improved: the glycosylated hemoglobin [(8.3±1.3)% vs. (6.8±0.5)%, t=9.00, P<0.05], fasting blood glucose [(7.7±0.8)mmol/L vs. (6.9±0.5)mmol/L, t=7.90, P<0.05] and 2-hour postprandial blood glucose[(11.4±2.1)mmol/L vs. (9.6±0.8)mmol/L, t=7.00, P<0.05] were significantly decreased. It is suggested that health education provided by the general practice team can standardize the insulin administration in diabetic patients and improve blood sugar control.

Studies on the relationship between intestinal factor and pulmonary lesion during shock / 中国病理生理杂志

The effects of intestinal factor on pulmonary lesion during shock were investigated. Anesthetized rabbits were dividcd at random into SMAO shock group(n=11) and sham shock group (n=8). Occlusion of SMA for 60 min followed by reperfusion produced a significant elevation of pulmonary capillary permeability index (PCPI), an increase of MDA in lung tissue, ultrastructural damage of type Ⅱ pneumocytes, and hyperemia, edema and haemorrhage in alveoli or bronchioli. There was a positive correlation between intestinal mucosal lesion and pulmonary lesion. However, PaO_2 showed no significant declination in this shock model. In vitro, the plasma collected from SMV blood of cats, which had been subjected to SMAO for 90 min, exerted a deleterious effect on isolated perfused rat lungs, characterized by elevation of pulmonary arterial perfusion presure and PCPI, increase in LDH and MDA in the perfusate. These results suggest that the humoral factors released from ischemic intestine into circulation may be, at least partially, accounted for the pulmonary damage during shock.