Facial processing in bipolar disorder is mediated by clinical and biological aspects

Objective: The process of detecting faces can be considered one of the initial steps in face recognition, which is essential for human interaction. We sought to investigate whether a face perception task reliably detects subtle perceptual disturbances between patients with bipolar disorder (BD) and healthy controls. Methods: In this multisite study, we examined differences between BD patients and matched healthy controls. Participants were instructed to detect the orientation (either left or right) of a face when it was presented as a face/non-face pair on a computer screen using Bayesian entropy estimation. Data analyses compared performance between the groups. Results: Overall, BD patients exhibited more perceptual disturbances compared with controls. BD patients who took olanzapine had better performance and faster reaction times (RTs) than patients who took lithium or were medication-naive. BD patients who took lithium had better performance and faster RTs than medication-naive patients. The medication-naive BD group exhibited greater disturbances than all other groups. Conclusion: These findings highlight the reliability of the face perception task used herein and may be important for public health initiatives and follow-up studies that seek to understand the diverse effects of other variables that can affect sensory processing in this population.

Self-face perception: Individual differences and discrepancies associated with mental self-face representation, attractiveness and self-esteem

Self-face perception plays an important role in self-consciousness and personal identity as well as in social exchanges and well-being. Despite its significance, little is known about how individuals represent their faces internally. This study explored mechanisms of self-face perception in three experiments. First, participants chose from two images (self-face image vs. self-image with manipulated facial features) which one was their veridical image and which one they liked most. Afterwards, participants could (digitally) manipulate their facial features to increase their attractiveness (either to themselves or to an imagined other/s). Results showed that self-face recognition was better when veridical faces were paired with 'clones' with larger facial features or when all facial features were enlarged concurrently. Moreover, up to half of the participants preferred smaller noses and larger eyes and manipulated their self-images accordingly. State (but not trait) self-esteem was inversely correlated with eye, mouth and nose size manipulations made to increase one's attractiveness. The results indicate that a certain tolerance for error in self-face recognition might be required to maintain a consistent facial identity during one's lifespan. The discovered preference for neotenous features and discrepancies between one's perceived and one's veridical face and their link to state self-esteem are discussed...