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1.
China Journal of Chinese Materia Medica ; (24): 347-351, 2020.
Artigo em Chinês | WPRIM | ID: wpr-1008343

RESUMO

Eight compounds were isolated from the ethyl acetate extraction of Prunus mume by column chromatography. On the basis of physicochemical properties and spectrum analysis, these compounds were identified as isoquercitrin-6″-O-benzoate(1), pinoresinol(2), naringin(3), ethyl-β-D-glucopyranoside(4), astragalin(5), quercetin(6), hypericin(7), and rutin(8). Among them, compound 1 was a new natural product, and compounds 2-5 were isolated from this plant for the first time. In vitro study, compounds 1, 3, 5-8 could significantly increase the cell survival ratio.


Assuntos
Acetatos , Compostos Fitoquímicos/análise , Extratos Vegetais/química , Prunus/química , Solventes
2.
China Journal of Chinese Materia Medica ; (24): 1392-1396, 2019.
Artigo em Chinês | WPRIM | ID: wpr-774544

RESUMO

Five compounds were isolated from the fibrous roots of Anemarrhena asphodeloides by silica gel, Sephadex LH-20 and semi-HPLC column chromatography. On the basis of physic-chemical properties and spectroscopic data analysis, these compounds were identified as methyl 2-[2,4-dihydroxy-3-(4-hydroxybenzoyl)-6-methoxyphenyl]acetate(1), 4-[formyl-5-(methoxymethyl)-1H-pyrrol-1-yl]butanoate(2), perlolyrine(3),syringaresinol-4'-O-β-D-glucoside(4) and 4',6-dihydroxy-4-methoxybenzophenone-2-O-(2″),3-C-(1″)-1″-desoxy-α-L-fructofuranoside(5). Among them, 1 was a new benzophenone. Compounds 2-5 were isolated from this plant for the first time. Compound 1 was tested for neuroprotective effects against H_2O_2-induced damage in SH-SY5 Y cells.


Assuntos
Humanos , Anemarrhena , Química , Benzofenonas , Farmacologia , Linhagem Celular , Cromatografia Líquida de Alta Pressão , Fármacos Neuroprotetores , Farmacologia , Compostos Fitoquímicos , Farmacologia , Raízes de Plantas , Química
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