RESUMO
Objective To discuss the clinical characteristics and treatment of amenorrhea caused by Tripterygium Wilfordii polyglycoside (TWP).Methods The sexual hormone levels of 25 outpatients of The First Affliated Hospital Of Wenzhou Medical College who suffered from secondary amenorrhea after the use of TWP were examined before and after the hormone therapy.In addition,the clinical presentations were observed.Results (1)The E2 level went down lower than 73.2pmol/L while FSH went up higher than 40U/L in all the 25 patients.Among them,24 patients were confirmed of the diagnosis of premature ovarian failure.⑵HT is an effective way for 20 patients.The total efficiency of the therapy was 80%.⑶The E2 secreted by ovary was higher (63.19?10.81)pmol/l vs. (365.45?161.60) pmol/L and FSH(110.72?21.52)U/L vs. 11.46?17.70)U/Lsecreted by pituitary was lower after therapy than before.⑷After the second period of therapy, the clinical perimenopausal symptoms of all the patients were improved to different degrees.Conclusion TWP may result in the disorders of ovarian functions, but and HT in time may be an effective therapy.
RESUMO
Objective To explore the feasibility of laparoscopic operations in the treatment of ovarian benign tumors. Methods A retrospective analysis of 150 cases of ovarian benign tumors treated by laparoscopic surgery (146 cases of oophorocystectomy and 4 cases of adnexectomy) from January 1997 to October 2003 was made. Results Surgery was completed successfully in all the 150 cases and no conversions to open surgery were required. Mild extraperitoneal emphysema was observed in 2 cases and no other complications occurred. The mean blood loss was 100 ml, the mean operation time was 80 min, and the mean length of hospitalization was 4 3 days. A total of 128 cases were followed up for a mean of 3 8 years. Recurrence was found in 4 cases in 38 cases of endometriosis cysts. Among 15 patients complicated with infertility, conception occurred in 6 patients after surgery, with a pregnancy rate of 40%. Conclusions Laparoscopic surgery is safe and effective for ovarian benign tumors provided patients are properly selected.