MUTAGENESIS OF STREPTOMYCES HYGROSCOPICUS NND-52 PRODUCING AZALOMYCIN B / 微生物学通报

Streptomyces hygroscopicus NND-52 producing Azalomycin B was treated with UV, UV -- LiC1, acridine orange ,the best treatment dose was determined. The yields of several strains which were obtained were more than three times thaat of CK, and the yield of strain A13 was 1100mg/L,they were stable. Through comparing the treating methods, it was shown that the later two methods were more effective

MUTAGENESIS OF STREPTOMYCES HYGROSCOPICUS NND-52 PRODUCING AZALOMYCIN B / 微生物学通报

Streptomyces hygroscopicus NND 52 producing Azalomycin B was treated with UV,UV+LiCl,acridine orange,the best treatment dose was determined. The yields of several strains which were obtained were more than three times thaat ofCK, and the yield of strain A13 was 1100mg/L,they were stable.Through comparing the treating methods, it was shown that the later two methods were more effective