Morphometry of submucous and myenteric esophagic plexus of dogs experimentally reinfected with Trypanosoma cruzi

We carried out a morphometric study of the esophagus of cross-bred dogs experimentally infected or consecutively reinfected with Trypanosoma cruzi 147 and SC-1 strains, in order to verify denervation and/or neuronal hypertrophy in the intramural plexus. The animals were sacrificed in the chronic stage, 38 months after the initial infection. Neither nests of amastigotes, nor myositis or ganglionitis, were observed in all third inferior portions of esophageal rings analyzed. No nerve cell was identified in the submucous of this organ. There was no significant difference (p>0.05) between the number, maximum diameter, perimeter, or area and volume of the nerve cells of the myenteric plexus of infected and/or reinfected dogs and of the non-infected ones. In view of these results we may conclude that the 147 and SC-1 strains have little neurotropism and do not determine denervation and/or hypertrophy in the intramural esophageal plexuses in the animals studied, independent of the reinfections

Avaliacao parasitologica e sorologica de caprinos inoculados experimentalmente pelo Trypanosoma cruzi / Serological and parasitological evaluation of goats experimentally inoculated with Trypanosoma cruzi

A infeccao experimental pelo Trypanosoma cruzi foi estudada em nove caprinos jovens. Os animais foram inoculados via intraperitoneal com 1000 tripomastigotas sanguineos/Kg de peso com as cepas 147 (Grupo 1) e 229 (Grupo 2), isoladas de pacientes chagasicos cronicos de Babui, MG. Realizaram-se exames de sangue a fresco, xenodiagnostico, hemocultura e sorologia (RIFI e ELISA)...