1.
Braz. j. infect. dis
;
19(6): 675-676, Nov.-Dec. 2015.
Artigo
em Inglês
| LILACS
| ID: lil-769624
2.
Braz. j. infect. dis
;
15(1): 69-73, Jan.-Feb. 2011. tab
Artigo
em Inglês
| LILACS
| ID: lil-576789
RESUMO
In 2008 isolates of KPC-producing Klebsiella pneumoniae (KPC-KPN) were detected for the first time at Hospital Heliópolis, São Paulo, Brazil. The aim of this study was to characterize the clinical and microbiological outcomes of infections caused by KPC-KPN. A historical cohort of patients from whom KPC-KPN strains were isolated was performed. Isolates were identified as resistant to ertapenem by automated broth microdilution system and screened as carbapenemase producers by the modified Hodge test. The beta-lactamase resistance gene blaKPC was detected by PCR. The genetic relatedness of isolates was determined by PFGE. The study provides early clinical experience in treating KPC-KPN infections in a Brazilian tertiary center.