RESUMO
This report describes a case of polycystic kidney disease in a male, mixed breed bovine aged one year. On clinical examination revealed a poor nutritional status, pallid mucous membranes, moderated dehydration (8 to 10%), ulcers on the ventral portion of the tongue, multifocal areas of hypotrichosis covered with scabs throughout the entire body and permanent sternolateral decubitus. The blood exam revealed aregenerative anemia and leukocytosis (neutrophilia) with deviation to the left. The necropsy revealed enlarged, pallid kidneys with a finely irregular natural surface. The histological analysis revealed the nearly complete replacement of the renal cortex by numerous small cysts, distension of the Bowman space, tubular regeneration, fibrosis, edema and mild interstitial lymphoplasmacytic inflammatory infiltrate. Keywords: diseases of cattle, kidney disease, lesions uremia, nephropathy