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3.
West Indian med. j ; 55(2): 89-94, Mar. 2006. tab
Artigo em Inglês | LILACS | ID: lil-472659

RESUMO

Critical donor selection and testing increases the safety of blood transfusion by excluding donors at risk of transmitting infections. This study investigated the seroprevalence of and risk factors for sexually transmitted infections (STIs) among accepted and deferred blood donors in Jamaica. A total of 1015 blood donors consisting of 794 (78) accepted donors and 221 (22) deferred donors presenting at the Central Blood Bank, Jamaica, over a six-month period, were recruited for this study. A standardized questionnaire was administered to each participant and a sample of blood obtained for detection of hepatitis B surface antigen, antibodies to Treponema pallidum, human immunodeficiency virus (HIV) and human T-cell lymphotrophic virus type-1 (HTLV-1). Deferred donors were three times more likely to be seropositive for STI than accepted donors (16.3vs 5.2, OR 3.57, 95CI 2.16 - 5.90, p < 0.0001). Males had significant association between STI seropositivity and having fathered children with two or more women (p = 0.0085), unprotected sexual intercourse with several persons (p = 0.0326), and history of genital herpes (p = 0.0121). Significant risk factors identified among females were unprotected sex with several partners (p = 0.0385); having more than ten lifetime partners (p = 0.0105); and use of depoprovera (p = 0.0028). This study confirms higher rates of STI among deferred blood donors and supports the donor deferral system in Jamaica.


La prueba y selección crítica del donante aumenta la seguridad de la transfusión de sangre, excluyendo a los donantes con riesgo de transmitir infecciones. Este estudio investigó la seroprevalencia de las infecciones transmitidas sexualmente (ITS) entre los donantes de sangre aceptados y diferidos en Jamaica. Un total de 1015 donantes de sangre consistente en 794 (78%) donantes aceptados, y 221 (22%) donantes diferidos que acudieron al Banco de Sangre Central en Jamaica por un periodo de seis meses, fueron reclutados para este estudio. A cada uno de los participantes se le aplicó una encuesta estandarizada, y se obtuvo una muestra de sangre para la detección del antígeno de superficie de la hepatitis B, los anticuerpos del Treponema pallidum, el virus de la inmunodeficiencia humana (VIH), y el virus linfotrópico humano de células T tipo 1 (HTLV-1). Los donantes diferidos presentaron una probabilidad tres veces mayor de ser seropositivos que los donantes aceptados (16.3% frente a 5.2%, OR 3.57, 95% CI 2.16 - 5.90, p <0.0001). En los varones se dio una asociación significativa entre la seropositividad de ITS y el haber engendrado hijos con dos o más mujeres (p = 0.0085), el intercambio sexual desprotegido con distintas personas (p = 0.0326), y una historia de herpes genitales (p = 0.0121). Los factores de riesgo significativos identificados entre las hembras fueron el sexo desprotegido con diferentes parejas (p = 0.0385), el haber tenido más de diez parejas a lo largo de su vida (p = 0.0105), y el uso de depoprovera (p = 0.0028). Este estudio confirma que las tasas de ITS entre los dotantes de sangre diferidos son más altas, y respalda el sistema de aplazamiento de donantes en Jamaica.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Doadores de Sangue , Infecções Sexualmente Transmissíveis/epidemiologia , Seleção do Doador , HIV , Anticorpos Antibacterianos/sangue , Anticorpos Antivirais/sangue , Antígenos de Superfície da Hepatite B/sangue , Análise de Variância , Infecções Sexualmente Transmissíveis/sangue , Infecções Sexualmente Transmissíveis/terapia , Estudos Soroepidemiológicos , Fatores de Risco , Jamaica/epidemiologia , Transfusão de Sangue , Treponema pallidum/isolamento & purificação , Vírus Linfotrópico T Tipo 1 Humano/isolamento & purificação
4.
West Indian med. j ; 54(5): 279-282, Oct. 2005. ilus
Artigo em Inglês | LILACS | ID: lil-472833

RESUMO

The subtypes of 141 isolates of human immunodeficiency virus type-1 (HIV-1) from Jamaica were determined by a combination of env and gag heteroduplex mobility analysis (HMA) genotyping. The majority of HIV-1 isolates were subtype B (131/141, 93.0); one (0.8) isolate each of subtypes C, D and E was found and 7 (4.9) were indeterminate. These results and the failure of the sets of primers used to amplify some of the HIV-1 isolates provide strong evidence of genetic diversity of the HIV/AIDS epidemic in Jamaica. Surveillance of the circulating HIV-1 genetic subtypes is a pre-requisite for developing regional vaccine strategies and understanding the transmission patterns of the virus. This is the first study of its kind in Jamaica and the findings complement data from other Caribbean countries. This work supports the view of colleagues from the French and Spanish-speaking Caribbean that an epidemiological network supported by regional laboratories will help track this epidemic accurately with positive outcomes for the public.


Los subtipos de 141 aislados del virus tipo 1 de la inmunodeficiencia humno (VIH-1) en Jamaica, fueron determinados combinando la genotipificación por análisis de heterodúplex (HMA) en los genes env y gag. La mayor parte de los aislados HIV-1 fueron del subtipo B (131/141, 93.0%), se halló uno (0.8%) aislado para cada uno de los subtipos C, D y E, en tanto que 7 (4.9%) fueron indeterminados. Estos resultados y el fallo de los conjuntos de primers usados para amplificar algunos de los aislados de VIH-1, ofrecen fuerte evidencia de la diversidad epidémica del VIH/SIDA en Jamaica. La vigilancia de los subtipos genéticos de VIH-1 en circulación, constituye un pre-requisito, tanto para desarrollar estrategias de vacunas a nivel regional, como para entender los patrones de transmisión del virus. Este es el primer estudio de este tipo en Jamaica, y nuestros hallazgos complementan los datos obtenidos en otros países del Caribe. Coincidimos con nuestros colegas del Caribe francófono e hispano-parlante en cuanto a que una red epidemiológica apoyada por los laboratorios regionales, nos ayudaría a continuar rastreando esta epidemia con exactitud, y con resultados positivos para el público.


Assuntos
Humanos , Masculino , Feminino , HIV-1 , Genes env , Genes gag , Infecções por HIV/epidemiologia , HIV-1 , Estudos de Amostragem , DNA Viral/análise , Incidência , Infecções por HIV/diagnóstico , Jamaica/epidemiologia , Medição de Risco , Países em Desenvolvimento , Reação em Cadeia da Polimerase/métodos , Sensibilidade e Especificidade
5.
West Indian med. j ; 54(1): 70-76, Jan. 2005.
Artigo em Inglês | LILACS | ID: lil-410072

RESUMO

The purpose of this study was to assess the prevalence of high risk health behaviours among adult Jamaicans aged 15-49 years in 2000, and to compare the results with the 1993 survey. A nationally representative sample of 2013 persons aged 15-74 years was surveyed in 2000 using cluster sampling in the Jamaica Healthy Lifestyle Survey (Wilks et al, unpublished). Interviewer administered questionnaires and anthropometrical measurements were done. Data for a sub-sample of adults aged 15-49 years were analyzed The sub-sample included 1401 persons (473 men and 928 women). Significantly more men (18.6) than women (4.3) reported never having had a blood pressure check (p = 0.0001). Approximately one-third of the women reported that they had never had a Pap smear (36.0) or a breast examination (31.2). Current cigarette smoking was reported in 28.6 of men and 7.7 of women (OR 3.73 CI 2.71, 5.15), while 49.0 of men and 15.0 of women ever smoked marijuana (OR 3.28 CI 2.56, 4.20). Significantly more men (28.0) than women (11.7) reported ever having a sexually transmitted disease (OR 2.93 CI 2.16, 3.97); having more than one sexual partner in the past year (49.1 vs 11.4, OR 4.31 CI 3.22, 5.76) and usually using a condom during sexual intercourse (55.3 vs 40.5, OR 1.3 CI 1.11, 1.68). Between 1993 and 2000, significant trends include: more persons reported having a blood pressure check, a reduction in multiple sexual partners, increased condom use at last sex (women), reduced crack/cocaine use (males) and increased marijuana smoking. Although there were some significant positive lifestyle trends between 1993 and 2000, high risk behaviours remain common among Jamaican adults. Comprehensive health promotion programmes are needed to address these risk behaviours


El propósito de este estudio fue evaluar la prevalencia de conductas de alto riesgo para la salud entre adultos jamaicanos comprendidos en las edades de 15 a 49 en el año 2000, y comparar los resultados con la investigación realizada en 1993. Una muestra nacional representativa de 2013 personas comprendidas en las edades de 15 a 74 años, fue sometida a investigación en el 2000, usando el muestreo por cluster del Jamaica Healthy Lifestyle Survey (Wilks et al, inédito). Se realizaron entrevistas en forma de cuestionarios, así como mediciones antropométricas. Se analizaron los datos de una sub-muestra de adultos entre edades de 15 a 49 años. La submuestra incluyó 1401 personas (473 hombres y 928 mujeres). Un número de hombres significativamente mayor (18.6%) que el de las mujeres (4.3%) reportaron no haber tenido nunca un chequeo de la presión (p = 0.0001). Aproximadamente un tercio de las mujeres reportó no haberse hecho nunca la prueba citológica (36.0%) o el examen de mamas (31.2%). El hábito actual de fumar cigarrillos fue reportado en el 28.6% de los hombres y el 7.7% de las mujeres (OR 3.73 CI 2.71, 5.15), mientras que el 49.0% de los hombres y el 15% de las mujeres nunca fumó marihuana (OR 3.28 CI 2.56, 4.20). Significativamente más hombres (28.0%) que mujeres (11.7%) reportaron no haber tenido nunca enfermedades de transmisión sexual (OR 2.93 CI 2.16, 3.97); haber tenido más de una pareja sexual en el año anterior (49.1% vs 11.4%, OR 4.31 CI 3.22, 5.76), y usar comúnmente condón durante el acto sexual (55.3% vs 40.5%, OR 1.3 CI 1.11, 1.68). Entre 1993 y 2000, las tendencias significativas incluyen lo siguiente: más personas reportaron el chequeo de la presión sanguínea, una reducción en las parejas sexuales múltiples, el aumento del uso de condones en el último acto sexual (mujeres), la reducción en el uso de crack/cocaína (hombres), y aumento en el consumo de marihuana para fumar. Aunque hubo algunas tendencias positivas significativas en cuanto al estilo de vida entre 1993 y el 2000, los comportamientos de alto riesgo siguieron siendo comunes entre los adultos jamaicanos. Se necesitan programas generales de la promoción de la salud para abordar estas conductas de alto riesgo.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Comportamentos Relacionados com a Saúde , Assunção de Riscos , Consumo de Bebidas Alcoólicas/epidemiologia , Infecções Sexualmente Transmissíveis/epidemiologia , Estilo de Vida , Fumar Maconha/epidemiologia , Jamaica/epidemiologia , Inquéritos Epidemiológicos , Tabagismo/epidemiologia , Transtornos Relacionados ao Uso de Substâncias/epidemiologia
6.
West Indian med. j ; 53(5): 322-326, Oct. 2004.
Artigo em Inglês | LILACS | ID: lil-410237

RESUMO

BACKGROUND: The study describes a cohort of HIV-infected Jamaican children receiving antiretroviral therapy (ART) and reports the outcome. METHOD: An observational prospective study was conducted on HIV-infected Jamaican children receiving anti retroviral drug therapy (ART). The outcome measures, weight, height, hospital admissions and length of stay were compared at initiation and within six months of commencing ART. RESULTS: There were 37 (33.6) of 110 HIV-infected children receiving ART during 2001 to 2003. The median age at commencement was six years (age range 1-16 years) with 54.1 (20) males and 48 AIDS orphans. Care was home-based for 68 of all cases with the University Hospital of the West Indies managing 27 (73) and the Bustamante Hospital for Children 10 (27). The distribution by Centers for Disease Control and Prevention (CDC) clinical class was C (severely symptomatic), 22 (59.5); B (moderately symptomatic), 8 (21.6); A (mildly symptomatic), 6 (16.2) and N (asymptomatic), one (2.7). Among 14 (36) children with CD4 counts, 8 (57) were CDC immune class 2 (moderate immunodeficiency) and 6 (43) were class 3 (severe immunodeficiency). After commencing ART the mean difference in admissions was--1.5+/-2.55 admissions (95 CI -2.3, -0.6; p < 0.001) and in length of stay was -12.9+/-21 day (95 CI -19.9, -0.5.9; p < 0.001). Antiretroviral therapy resulted in a mean weight gain of 2.8 kg+/-4.9 kg (95 CI 1.0, 4.5; p < 0.003) and a mean gain in height of 1.7 cm+/-2.6 cm (95 CI 0.6, 2.8; p < 0.003). Five children required second line therapy. CONCLUSION: The introduction of antiretroviral therapy has resulted in improved outcomes and is being initiated in older children cared for mainly at home. Limitations in accessing affordable second line agents underscore the need for compliance with first line therapy


Assuntos
Humanos , Masculino , Feminino , Lactente , Pré-Escolar , Criança , Adolescente , Terapia Antirretroviral de Alta Atividade , Antirretrovirais , Infecções por HIV/tratamento farmacológico , Resultado do Tratamento , Serviços de Saúde da Criança , Estudos Prospectivos , Infecções por HIV/classificação , Infecções por HIV/fisiopatologia , Jamaica , Índice de Gravidade de Doença
7.
West Indian med. j ; 53(5): 315-321, Oct. 2004.
Artigo em Inglês | LILACS | ID: lil-410238

RESUMO

OBJECTIVE: To document the frequency of Centers for Disease Control and Prevention (CDC)-defined clinical conditions, opportunistic and co-infections among children with HIV/AIDS. METHODS: This prospective, observational study reports the findings of 110 HIV-infected children followed in multicentre ambulatory clinics during September 1, 2002, to August 31, 2003, from the 239 children enrolled in the Kingston Paediatric and Perinatal HIV/AIDS Programme, Jamaica. We describe the clinico-pathologic characteristics of these children with HIV/AIDS, using the CDC criteria. RESULTS: The client distribution by clinic site was as follows: the University Hospital of the West Indies, 71 (64.6), Bustamante Hospital for Children, 23 (20.9), Comprehensive Health Centre 13 (11.8/) and Spanish Town Hospital, 3 (2.7). The median age of the 110 children with HIV/AIDS was 6.0 years (range 0.9-17.5). Mode of transmission was primarily mother-to-child (88.0) and only 4 maternal/infant pairs received antiretroviralprophylaxis. Grouped by CDC category: 17 (15.4) were asymptomatic (N), 22 (20.0) mildly symptomatic (A), 30 (27.3) moderately symptomatic (B) and 41 (37.3) severely symptomatic (C). The most common CDC-defining symptoms were lymphadenopathy (12, 42.8) and asymptomatic (6, 21.4) in category N; lymphadenopathy (30, 29.7), dermatitis (20, 19.8) and persistent or recurrent upper respiratory tract infections (20, 19.8) in category A; bacterial sepsis (18, 34.6) and recurrent diarrhoea (11, 21.2) in category B; and wasting (28, 30.0), encephalopathy (26, 27.9), and serious bacterial infections (15, 16.1) in category C; Pulmonary tuberculosis (7, 7.5) and Pneumocystis (jiroveci) carinii pneumonia; (5, 5.4) were the most frequent opportunistic infections. Streptococcus pneumoniae (10, 30.3) was the most common invasive bacterial pathogen causing sepsis and Escherichia coli (14, 34.2) was the most common bacterial pathogen causing urinary tract infections, among the cohort. Thirty-three per cent commenced antiretroviral drugs (ARVs). There were 57 hospitalizations and five deaths. CONCLUSIONS: The study is an important step toward documentation of the natural history of paediatric HIV/AIDS in a primarily ARV-naive population from a developing country. It promotes training in paediatric HIV management as we move toward affordable access to antiretroviral agents in the wider Caribbean and the implementation of clinical trials


Assuntos
Humanos , Masculino , Feminino , Lactente , Pré-Escolar , Criança , Adolescente , Infecções Oportunistas Relacionadas com a AIDS/epidemiologia , Infecções por HIV/epidemiologia , Transmissão Vertical de Doenças Infecciosas , Progressão da Doença , Centers for Disease Control and Prevention, U.S. , Estados Unidos , Estudos Prospectivos , Fatores de Risco , Infecções por HIV/patologia , Infecções por HIV/transmissão , Jamaica/epidemiologia , Prevalência , Síndrome da Imunodeficiência Adquirida/epidemiologia , Síndrome da Imunodeficiência Adquirida/patologia , Síndrome da Imunodeficiência Adquirida/transmissão
8.
West Indian med. j ; 53(5): 308-314, Oct. 2004.
Artigo em Inglês | LILACS | ID: lil-410239

RESUMO

BACKGROUND: In a few Caribbean islands, prevention of mother-to-child transmission (pMTCT) of HIV with zidovudine prophylaxis has reduced transmission rates from 27 - 44 to 5.5 - 9 . OBJECTIVES: To highlight the uptake of interventions, preliminary outcomes and challenges in caring for HIV-exposed infants in a pMTCT HIVprogramme in a resource-limited setting. METHOD: A cohort of HIV-infected pregnant women were identified at the leading maternity centres in Greater Kingston through HIV counselling and testing and enrolled in the Kingston Paediatric and Perinatal HIV/AIDS Programme. Antiretroviralprophylaxis with zidovudine or nevirapine was given to the HIV-positive women and their newborns along with formula feeding. Some infants were enrolled retrospectively and followed irrespective of whether they had or had not received antiretroviral prophylaxis. A multidisciplinary team at the paediatric centres supervised protocol-driven management of the infants. Infants were followed for clinical progress and definitive HIV-infection status was to be confirmed at 18 months of age by ELISA or the Determine Rapid Test. RESULTS: During September 1, 2002 through August 31, 2003, 132 HIV-exposed infants were identified. For those infants prospectively enrolled (78), 97 received antiretroviral prophylaxis and 90 were not breastfed For all HIV-exposed children, 90 received cotrimoxazole prophylaxis and 88 continued follow-up care. Ninety-two per cent of all the infants remained asymptomatic and five died; of these deaths one is possibly HIV-related (severe sepsis at 11 weeks). This infant was retrospectively identified, had received no antiretroviral prophylaxis and was breastfed The main programme challenges, which were overcome, included the impact of stigma, compliance with antiretroviral chemoprophylaxis, breast-milk substitution and follow-up care. Financial constraints and laboratory quality assurance issues limited early diagnosis of HIV infection. CONCLUSION: Despite the challenges, the expected outcome is to prevent 50 new cases of HIV/AIDS in children living in Greater Kingston per year (300 over six years)


Assuntos
Humanos , Feminino , Gravidez , Recém-Nascido , Lactente , Transmissão Vertical de Doenças Infecciosas , Aceitação pelo Paciente de Cuidados de Saúde , Antibioticoprofilaxia , Cuidado Pré-Natal , Cuidado do Lactente , Infecções por HIV/prevenção & controle , Nevirapina/uso terapêutico , Resultado do Tratamento , Zidovudina/uso terapêutico , Estudos Prospectivos , Estudos Retrospectivos , Infecções por HIV/epidemiologia , Infecções por HIV/transmissão , Jamaica/epidemiologia
9.
West Indian med. j ; 53(5): 303-307, Oct. 2004.
Artigo em Inglês | LILACS | ID: lil-410240

RESUMO

BACKGROUND: In the face of the continuing pandemic of HIV/AIDS, the burden of the disease is now largest in the resource-poor developing world. The Joint United Nations Programme on HIV/AIDS (UNAIDS) has listed the adult prevalence rate for the Caribbean as second only to Sub-Saharan Africa. OBJECTIVE: To document the socio-demographic characteristics of paediatric and perinatal HIV/AIDS in Kingston, Jamaica. METHODS: A cohort of HIV-infected pregnant women were identified at the leading maternity centres in Kingston and St Catherine and were enrolled in the Kingston Paediatric and Perinatal HIV/AIDS Programme. Infants born to mothers within the programme were prospectively enrolled. Infants and children identified after delivery, whether HIV-exposed or infected, were also enrolled (retrospective group). All were followed according to standardized protocols. RESULTS: We report on a total of 239 children, 78 (prospective group) and 161 (retrospective group). Among the retrospective group, 68 were classified as infected. For the prospective group, the patients were recruited within twenty-four hours of birth in 98.7 of cases, whereas in the retrospective group, the median age of recruitment was 2.6 years. The median age of the mother was 27 years and that of the father was 33 years. There were seven teenage mothers. Twenty-six per cent of the children were in institutional care. Family size ranged from one to nine children--the median was two children. For those parents where occupation was reported, the majority held semi-skilled or unskilled jobs. Patients attended their regional clinics. CONCLUSION: HIV/AIDS represents a significant human and financial burden on a developing country such as Jamaica and this underscores the need for urgent and sustained interventions to stem the epidemic


Assuntos
Humanos , Feminino , Gravidez , Recém-Nascido , Lactente , Pré-Escolar , Classe Social , Infecções por HIV/epidemiologia , Soropositividade para HIV/epidemiologia , Efeitos Psicossociais da Doença , Transmissão Vertical de Doenças Infecciosas , Progressão da Doença , Estudos Prospectivos , Estudos Retrospectivos , Fatores Socioeconômicos , Fatores de Risco , Incidência , Infecções por HIV/prevenção & controle , Jamaica/epidemiologia , Prevalência
10.
West Indian med. j ; 53(5): 297-302, Oct. 2004.
Artigo em Inglês | LILACS | ID: lil-410241

RESUMO

BACKGROUND: The seroprevalence of HIV among pregnant women in the Caribbean is 2-3 and increasing. The Kingston Paediatric and Perinatal HIV Programme is developing and implementing a unified programme to eliminate mother-to-child transmission (MTCT) of HIV in Kingston, Jamaica. METHODS: Pregnant women presenting to Kingston Metropolitan Antenatal Clinics, Victoria Jubilee Hospital, Spanish Town Hospital and the University Hospital of the West Indies had HIV serology performed by ELISA, or by the new Determine Rapid Test after receiving group counselling. HIV-positive women were referred to High Risk Antenatal Clinics. Antiretroviral prophylaxis with zidovudine (AZT), or nevirapine was given. Care was administered using a standard protocol by a multi-disciplinary team of public and academic healthcare personnel. RESULTS: In year one, 19,414 women delivered Among 14,054 women who started antenatal care for this period, 5,558 (40) received group counselling and 7,383 (53) received HIV-testing. During the fourth quarter of follow-up, these comparative rates were 66 (2049/3 118) and 72 (2260/3118) respectively. HIV seroprevalence overall was 2.1 (152/7 383). One hundred and seven HIV+ women at varying gestational ages were identified in the programme, 72 had so far received AZT and nine nevirapine (76). 0f 84 deliveries, birth outcomes were 75 live births (89), six neonatal deaths and four maternal deaths (all from HIV/AIDS). Major challenges include repeat pregnancies of 36 despite prior knowledge of HIV seropositivity and poor partner notification with only 30 (32) having a HIV-test. Although rates of HIV testing in pregnant women in Greater Kingston are increasing, rates of testing overall remain sub-optimal. On the labour ward, there was sub-optimal identification of the HIV+ pregnant woman and administration of AZT chemoprophylaxis, along with issues of patient confidentiality and stigma. CONCLUSION: This programme needs strengthening in order to reduce maternal-fetal transmission of HIV in Greater Kingston, Jamaica [quot]pMTCT-PLUS, or comprehensive family-centred care, is the next step[quot]


Assuntos
Humanos , Feminino , Gravidez , Adolescente , Adulto , Transmissão Vertical de Doenças Infecciosas , Avaliação de Programas e Projetos de Saúde , Complicações Infecciosas na Gravidez/prevenção & controle , Cuidado Pré-Natal , Infecções por HIV/prevenção & controle , Soroprevalência de HIV , Assistência Perinatal , Complicações Infecciosas na Gravidez/epidemiologia , Infecções por HIV/epidemiologia , Infecções por HIV/transmissão , Jamaica/epidemiologia , Nevirapina/administração & dosagem , Resultado da Gravidez , Soropositividade para HIV , Zidovudina/administração & dosagem
11.
West Indian med. j ; 53(5): 293-296, Oct. 2004.
Artigo em Inglês | LILACS | ID: lil-410242

RESUMO

OBJECTIVES: This study aims to determine the number and age distribution of pregnant women testing positive for HIV at 16 selected clinics in Jamaica between 2001 and 2002; the utilization of therapeutic interventions to minimize the risk of mother-to-child transmission (MTCT) and the current status of the HIV-exposed infants and, finally, the number of children who received testing for detection of HIV and to calculate the incidence of MTCT in these children. METHODS: A retrospective study was carried out at sixteen pilot clinic sites by examining the patient records for all confirmed HIV-positive pregnant mothers and the resultant infants at these facilities for the period January 2001 to December 2002. RESULTS: One hundred and twenty-three of 8116 pregnant women newly tested positive during the period January 2001 to December 2002; however, 176 HIV+ women delivered. Fifty-three (30) knew their HIV status prior to participating in the programme. Sixty-two (1.4) and 61 (1.6) tested positive in 2001 and 2002, respectively. One hundred and ten (77) and 113 (83) mothers and infants, respectively, received ARV therapy, (92 - nevirapine, 8 - zidovudine). Twenty-three per cent of pregnant women received no ARV Forty-four (25.0) of the 176 infants had a documented ELISA HIV test before eighteen months of age, none had a PCR test. The health status of 40 (23) of these children was known: 30 (75) were alive and well, five of whom did not receive any ARV, one (2.5) was alive and ill and nine (22.5) were reported dead, five of whom received ARV; 28.6 of infants who did not receive ARV were reported as either dead or ill compared to 13.8 of those receiving ARV CONCLUSION: Though the majority of pregnant women discovered their HIV status during pregnancy, a significant number got pregnant knowing that they were HIV+. The majority of mothers and infants received ARV but the follow-up and testing of infants was limited. Nevirapine is clearly protective in the prevention of MTCT of HIV and should be made universally accessible. All infants delivered to HIV+ mothers should be identified and tested for HIV


Assuntos
Humanos , Feminino , Gravidez , Recém-Nascido , Transmissão Vertical de Doenças Infecciosas , Avaliação de Programas e Projetos de Saúde , Complicações Infecciosas na Gravidez/prevenção & controle , Cuidado Pré-Natal , Infecções por HIV/prevenção & controle , Instituições de Assistência Ambulatorial , Assistência Perinatal , Complicações Infecciosas na Gravidez/diagnóstico , Complicações Infecciosas na Gravidez/epidemiologia , Comportamento de Escolha , Estudos Retrospectivos , Infecções por HIV/diagnóstico , Infecções por HIV/epidemiologia , Jamaica , Medição de Risco , Prevalência , Projetos Piloto , Sorodiagnóstico da AIDS
12.
West Indian med. j ; 53(5): 277-282, Oct. 2004.
Artigo em Inglês | LILACS | ID: lil-410244

RESUMO

The global HIV/AIDS epidemic continues to grow at an alarming rate. The Caribbean has the second highest HIV prevalence rates after sub-Saharan Africa. In Jamaica, annual AIDS case rates continue to increase, especially in St James. The epidemic is predominantly heterosexual with an estimated HIV prevalence of 1.5 among adults. A comprehensive HIV/STI control programme has resulted in a safe blood supply, high awareness of HIV/AIDS and how to prevent it, increased condom use and a significant decline in syphilis rates. However, a number of social factors, including the strong stigma associated with AIDS, facilitate continued HIV spread and impede effective control. The national response must be significantly strengthened by ensuring appropriate social policies, combating stigma, scaling up prevention, providing antiretroviral treatment and developing a timely multi-sectoral response


Assuntos
Humanos , Masculino , Feminino , Controle de Doenças Transmissíveis , Infecções por HIV/epidemiologia , Programas Nacionais de Saúde , Atitude Frente a Saúde/etnologia , Desenvolvimento de Programas , Fatores Socioeconômicos , Heterossexualidade/estatística & dados numéricos , Infecções por HIV/prevenção & controle , Jamaica/epidemiologia , Liderança , Pobreza , Prevalência , Região do Caribe/epidemiologia , Síndrome da Imunodeficiência Adquirida/epidemiologia
15.
West Indian med. j ; 51(2): 97-101, Jun. 2002.
Artigo em Inglês | LILACS | ID: lil-333281

RESUMO

A survey of Essential National Health Research (ENHR) was conducted between December 1997 and November 1998 in nine developing countries. A total of 27 respondents from seven South East Asian and two Caribbean countries completed questionnaires. Respondents included 14 men and 13 women with a median age of 48 years (range 25-69 years); 15 were researchers, seven were health providers, three policy makers and one a community representative (one no response). ENHR was formally adopted in five countries mainly through public policy statements. Seven countries had a mechanism in place for promotion of ENHR and national meetings were held in five countries in the year prior to the survey. A special activity was conducted in order to define health research priorities in eight countries and a list of these priorities was available in seven countries. The level of ENHR activity was ranked as low or moderate in most countries except India and Malaysia which were rated as moderate to high. Three countries reported that the process resulted in new or additional funds being made available for research, while India reported available funds being reallocated to meet the priorities defined. The respondents of six countries said that ENHR networking had led to tangible results, including improved collaboration among researchers and research institutions and the sharing of resources among different organizations (five countries). The ENHR process had resulted in research findings being used to formulate or change health policy in five countries. Most countries had not produced any new research protocols through the ENHR process. However, there were 250 new research protocols in India and 68 in Pakistan, of which 20 and between 25 and 35, respectively, were funded and 15 peer reviewed articles had been published from India. This survey does suggest that the ENHR process may be promoting health research on priority health problems and the use of results to formulate policy in selected countries. However, it is too early to assess the contribution of ENHR to health and development and a variety of different studies would be needed to conduct this assessment.


Assuntos
Humanos , Pesquisa , Países em Desenvolvimento/estatística & dados numéricos , Inquéritos e Questionários
16.
West Indian med. j ; 50(Supl.4): 15-22, Sept. 2001.
Artigo em Inglês | LILACS | ID: lil-333356

RESUMO

Health trends in Jamaica have improved considerably during the past century. Life expectancy at birth increased from 38 years in 1900 to 72 years in 2000. The crude death and infant mortality rates declined significantly from 35.7 and 174.3 deaths to 5.1 and 24.4 deaths, respectively, in the same period. The seven leading causes of death in 1945 were infectious diseases while the main causes of mortality and morbidity are now the chronic non-communicable lifestyle diseases, and injuries. Over the past few decades, considerable progress has been made in controlling vaccine preventable diseases and eliminating poliomyelitis and measles. Rates of infectious syphilis, congenital syphilis and gonorrhoea have declined significantly in recent years although chlamydia and herpes are common and the HIV/AIDS epidemic is a growing concern. Over the past few decades health expenditure has grown more rapidly in the private health sector than in the public health sector although services in the public sector are provided at significantly lower cost. Jamaica provides good health at low cost. However, more funds are needed to support the public health system. The current health reform process needs to be informed by a better understanding of the factors that have contributed to Jamaica's achievements in health and needs a clear health focus. The Ministry of Health has articulated a vision of health for the 21st century that requires a significant reorientation of health staff as well as empowering people to take responsibility for adopting healthy lifestyles.


Assuntos
Humanos , Previsões , Saúde Pública/tendências , Morbidade , Mortalidade , Jamaica , Condições Sociais/economia , Condições Sociais/tendências , Doenças Transmissíveis/epidemiologia , Gastos em Saúde/tendências , Indicadores Básicos de Saúde , Reforma dos Serviços de Saúde/tendências , Síndrome da Imunodeficiência Adquirida/epidemiologia
18.
West Indian med. j ; 48(1): 9-15, Mar. 1999.
Artigo em Inglês | LILACS | ID: lil-473127

RESUMO

A population based probability sample of 958 persons (454 males and 504 females) aged 15 to 49 years was surveyed in Jamaica in late 1993 for lifestyle and behaviour risk factors. Demographic characteristics of the sample were comparable to the general population, 60of persons visited a private doctor the last time that they were ill. Based on self-reporting, 18of the women and 8of the men were hypertensive and 4.8of the women and 3.3of the men were diabetic. 26of the men and 8of the women had never had their blood pressure taken. 40of the women had never had a Papanicolaou smear, 29had never had a breast examination and 33said that they were overweight compared with 18of men. Smoking cigarettes and marijuana was more common among men (36) than women (11), as were drinking alcohol (79of men, 41of women) and heavy alcohol use (30of men, 9of women). Injuries requiring medical attention in the previous five years were reported by 40of the men and 15of the women. 34of the men and 12of the women regularly carried a weapon and 18of the sample had participated in or witnessed at least one violent act in the previous month. Most of the people interviewed used a contraceptive method; 10were not sexually active. Significantly more men than women had two or more sexual partners in the previous year (54vs 17, p < 0.001) or reported ever having a sexually transmitted disease (29vs 9, p < 0.001). Younger persons were more sexually active and more likely to use condoms during their most recent sexual intercourse. Higher socio-economic status and educational level generally had a more positive effect on health behaviour. This survey provides vital information relevant to planning health promotion campaigns and assessing their success.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Atitude Frente a Saúde , Comportamentos Relacionados com a Saúde , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Assunção de Riscos , Comportamento Contraceptivo , Consumo de Bebidas Alcoólicas/epidemiologia , Diabetes Mellitus/epidemiologia , Infecções Sexualmente Transmissíveis/epidemiologia , Esfregaço Vaginal/estatística & dados numéricos , Estilo de Vida , Fatores Sexuais , Fatores de Risco , Ferimentos e Lesões/epidemiologia , Hipertensão/epidemiologia , Fumar Maconha/epidemiologia , Jamaica/epidemiologia , Neoplasias da Mama/epidemiologia , Obesidade/psicologia , Parceiros Sexuais , Tabagismo/epidemiologia , Vigilância da População
19.
West Indian med. j ; 47(supl.4): 13-15, Dec. 1998.
Artigo em Inglês | LILACS | ID: lil-473383

RESUMO

On the fortieth anniversary of the Department of Social and Preventive Medicine, now renamed the Department of Community Health and Psychiatry, the contribution of the Department to the development of public health in Jamaica is briefly reviewed. The paper focuses on the challenges, goals and aspirations for the development of a [quot ]new[quot ] public health. The challenges include the need for more effective public health leadership, health promotion, better management of the health services and health reform. The latter should provide greater autonomy for the health regions and alternate ways of financing health, and should improve the quality of services provided. The Department is challenged to contribute by establishing a Public Health Residency Programme for doctors leading to a Doctor of Medicine or Doctorate in Public Health; to ensure that epidemiology becomes a basic science in the undergraduate medical curriculum, and that research plays a significant role in postgraduate training of clinical specialists; and to participate more actively in the actual practice of public health. A vision for health in the twenty-first century is given.


Assuntos
Humanos , Saúde Pública/tendências , Administração de Serviços de Saúde , Apoio Financeiro , Currículo , Educação de Graduação em Medicina , Epidemiologia/educação , Internato e Residência , Jamaica , Pesquisa/educação , Previsões , Promoção da Saúde , Qualidade da Assistência à Saúde , Reforma dos Serviços de Saúde , Saúde Pública/economia , Saúde Pública/educação
20.
West Indian med. j ; 47(3): 89-93, Sept. 1998.
Artigo em Inglês | LILACS | ID: lil-473405

RESUMO

A profile of health research in Jamaica between 1991 and 1995 was prepared in order to examine research capacity and needs as part of the process of promoting essential national health research. Of 43 organisations and research groups surveyed, 29 met the criterion of at least one peer reviewed publication between 1991 and 1995, and there were 201 health researchers. Most of the research groups had fewer than 20 professional staff with less than 10 engaged in health research. Institutional objectives and funding opportunities largely determined research priorities. 704 research papers were published over the period with 10 of the organisations responsible for 469 (66.6). The number of research papers is overestimated because the same paper may be reported by more than one research group due to multiple authorship. On the whole, local research groups appear to be small, vulnerable, under-funded and deficient in basic equipment as well as trained and experienced researchers and support staff. These are compelling reasons for health researchers to come together to tackle common problems, promote collaboration and forge a joint strategy to strengthen health research capability in Jamaica.


Assuntos
Humanos , Masculino , Feminino , Pesquisa sobre Serviços de Saúde/estatística & dados numéricos , Publicações/estatística & dados numéricos , Apoio à Pesquisa como Assunto , Bases de Dados como Assunto , Academias e Institutos/estatística & dados numéricos , Jamaica , Organizações de Planejamento em Saúde/estatística & dados numéricos , Pesquisa sobre Serviços de Saúde , Prioridades em Saúde
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