Sudden unexpected death in Parkinson's disease: Insights from clinical practice

Abstract Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common movement disorder. In the last decade, despite advances in treatment, mortality rates linked with PD continued to reach significant figures. Available studies have shown that compared with healthy controls, patients with PD are accompanied by high rates of premature death. This is usually caused by factors such as pneumonia and cerebrovascular and cardiovascular diseases. Recently, it has been demonstrated that a significant proportion of patients with PD die suddenly. This is referred to as a sudden and unexpected death in PD (SUDPAR). Here, we focus on the magnitude of SUDPAR. Finally, it is important to learn more about SUDPAR for the implementation of effective prevention strategies.

Extrapulmonary onset manifestations of COVID-19

Coronavirus disease (COVID-19) usually starts with pulmonary signs and symptoms. However, in some cases, the initial clinical presentations are extrapulmonary. This literature review aimed at summarizing and discussing the extrapulmonary onset manifestations of COVID-19. The most frequent initial extrapulmonary manifestations include hypogeusia, hyposmia, non-specific abdominal symptoms, corneal congestion, and deep venous thrombosis. Several rarer extrapulmonary manifestations in locations such as the brain, peripheral nerves, muscles, eyes, ears, myocardium, intestines, skin, or vessels have been additionally reported as onset presentations of COVID-19. In conclusion, it is crucial for clinicians and health care providers to consider extrapulmonary presentations at the onset of COVID-19 to avoid overlooking the infection and contributing to the spread of the disease.

Caracterizaçäo dos níveis de pressäo sonora em academias de ginásticas e queixas apresentadas por seus professores / Characterization of sound pressure levels in fitness centers and complaints from instructors

Este estudo objetiva identificar as queixas auditivas e orgânicas dos professores de ginástica e avaliar os níveis de pressão sonora (NPS) produzidos nas aulas de ginástica com música. A medição dos NPS foi realizada seguindo as condições sugeridas pela Associação Brasileira dc Normas Técnicas (ABNT), na Norma 10151. Forma de estudo: Prospectivo clínico randomizado. Material e método: 32 professores de ginástica responderam a um questionário com questões referentes as queixas relacionadas aos NPS. Resultados: As queixas mais frequentes foram: zumbidos (24 por cento), sensação de ouvido tampado (15 por cento)e baixa concentração (15 por cento). As modalidades de ginástica nas quais foi realizada a avaliação dos níveis de pressão sonora foram: Step, Body Pump e Aerofitness. Conclusão: Os resultados desta avaliação revelaram intensidades que variaram de 73,9 a 94,2 dBA e sugerem presença de elevados níveis de pressão sonora em 66 por cento das aulas avaliadas