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Journal of Breast Cancer ; : 131-140, 2019.
Artigo em Inglês | WPRIM | ID: wpr-738409

RESUMO

When faced with a case of bilateral breast cancer (BBC), understanding how to differentiate bilateral primary breast cancer from contralateral metastatic breast cancer is essential for treatment, but clear identification criteria have not been established to date. Diverse events play different roles in the therapy and prognosis of BBC; hence, it is of great significance to detect a more comprehensive and convincing technique to make an accurate differential diagnosis. We report a rare case of synchronous BBC in a 61-year-old Chinese woman. Based on her clinical and pathological features and the use of whole exome sequencing and cancer genome analysis, we concluded that the patient developed contralateral metastatic breast cancer which metastasized from left to right. Therefore, together with clinical, pathological and cancer genomics information, we could precisely define the origin and evolution of BBC.


Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Povo Asiático , Neoplasias da Mama , Mama , Diagnóstico , Diagnóstico Diferencial , Exoma , Genoma , Genômica , Metástase Neoplásica , Prognóstico
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