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Objective:To comparative study the clinical effect of combined spinal-epidural anesthesia and combined epidural anesthesia in uterine myomectomy.Methods:Totally 90 cases of patients with uterine myomectomy in our hospital from March 2012 to March 2013 were randomly divided into observation group and the control group, 45 patients in the control group were given epidural anesthesia, and observation group were given combined spinal-epidural anesthesia. BP, HR and surgical traction reaction were monitored in the operation and the effects of anesthesia and adverse events of the two groups were compared.Results: (1) Blood pressure of patients in two groups was decreased during anesthesia. Systolic pressure (x2=5.232,P<0.01) and diastolic blood pressure (x2=6.251,P<0.05) of patients in observation group were lower than control groups. The difference was statistically significant. (2)Patients of observation group showed shorter anesthesia onset time (x2=6.278,P<0.05) and completing time (x2=9.674,P<0.05), lower local anesthetics dosage (x2=12.256,P<0.05), better evaluation of anesthesia, and fewer adverse reactions. The difference was statistically significant (x2=16.576,P<0.01). (3)Anesthesia excellent rate in observation group were higher than that of control group, the difference was statistically significant (P<0.01).Conclusion: Combined spinal-epidural anesthesia has better anesthesia effects in uterine myomectomy than epidural anesthesia. And it is a worthy use of anesthesia.
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Objective To assess boron intake through food and drinking water for the people living in the boron industrial area.Methods Workers from boron mining and processing plants were selected as the exposure group,the other workers from the area where was near to the boron industrial area were selected as the community control group and peoples from the area where was far from boron industrial area were selected as the background control group,all the subjects were healthy adult men,Jul.2003-Sep.2004.Total 24 h food and drinking water of the subjects were collected,the boron concentrations and daily boron intake were analyzed.Results Boron concentrations of drinking water for the workers from boron mining area,community control group and background control group were 2.05,0.86 and 0.05 mg/L respectively;the food boron concentrations of the three groups were 9.46,6.19 and 3.29 mg/kg(DW)respectively;and daily boron intake through food and water were 8.00,4.25 and 1.40 mg/d respectively.The workers drinking the water from the staff canteen well and having dinner in this canteen had 95.5-469 mg/d boron exposure through food and water with average of 219.0 mg/L which was much higher than that of the other people and even closed to the LOAEL(lowest observed adverse effect level)of animals.Conclusion The risk of boron exposure for workers from boron mining and processing area is much higher than that of the other people.
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Objective To study the association between adults'respiratory health and elements concentrations in aerometric particulate matters and provide information about the effect of air pollution sources on human health. Methods Health question nairs were administered to 7 661 male and 7 673 female adults in 4 Chinese cities. 42 elements in particulate matters of both urban and rural areas were analyzed by XRF. The data were analyzed by using two-stage regression, the Logistic regression for the first stage and weighted linear regression for the other. Adult's respiratory health parameters were obtained by 1st stage analysis. The association of the elements in PM and adults'respiratory health parameters of 8 sites in the 4 cities was established. Odds ratios were given using the weighted linear regression model. Results Positive associations between adults'respiratory health and crust elements (Al, Ca, Fe, Si, Ti) and pollution elements (As, Ni, Cd, Pb) in PM2.5-10 or PM2.5 were found (OR=1.00-1.12). Associations of respiratory health parameters with elements in fine particle (OR=1.03-1.61) were stronger than those with elements in coarse particle (OR=1.03-1.12) in the case of the equal element concentrations. Conclusion An assumption of 'crust particle groups' was brought forward to give an explanation to the relation between crust elements and respiratory health. It assumed that the relation is an indirect one, since 'crust particle groups' in PM act as carrier of toxic matters and/or bacteria. The result points out that it should pay much attention to controlling of PM from soil as well as controlling of industrial pollution.