Study on pulverization and extraction of Huanglianjiangtang Tablets / 中成药

AIM: To make the optimum process conditions of extracting and grinding for Huanglianjiangtang Tablets (Rhizoma Coptidis, Radix et Rhizoma Rhei, etc.). METHODS: Applying fluid jet mill to the root of Radix et Rhizoma Rhei and adopting emodin and chrysophanol as markers, degree of grinding on herbs was studied, optimum extraction of Rhizoma coptidis with Berberine as marker was investigated by orthogonal design. RESULTS: Optinum processing condition was as follow, powdered herbs with diameter less than 10?m macerated in 50% ethanol for 40min , reflux extraction three times and 2hr per time. CONCLUSION: The optimum processes result in high content of active constituents. These processes can be applied rightly in mass production.