RESUMO
The comprehensive paper of thyroid Hurthle cell neoplasms(NCNs) is made on the literatures review.This paper reveals the follows:(1)HCNs differ significantly from follicular neoplasms on a molecular level;(2)Clinical and morphological parameters were not helpful in predicting recurrence and in differentiating benign from malignancy neoplasms;(3) The treatment of choice for adenoma is lobo-isthmectomy. For malignant Hurthle cell tumor, total thyroidectomy is the most rational treatment associated with cervical lymphadenectomy in the presence of matastatic nodes. In all cases, long-term periodical follow-up should be done; (4)HCNs represent a pathological entity;(5)The criteria of differentiating adenoma from carcinoma needs further investigation to guide the clinical treatment ;(6)Treatment process of HCNs should be individualized according to the clinical and histopathological results.