RESUMO
We report a case of severe perinatal asphyxia with both cerebral venous thrombosis and adrenal hemorrhage who survived with severe sequela including multicystic encephalomalasia, acquired microcephaly and blindness. Hematological investigations showed normal levels of anticardiolipin antibodies, protein C and S levels and activity, antithrombin III levels. Factor V Leiden mutation was negative. The adrenal hemorrhage resolved within three months with glucocorticoid therapy, the cerebral venous thrombosis resolved within two months without treatment. The literature on neonatal cerebral venous thrombosis is also reviewed.
Assuntos
Doenças das Glândulas Suprarrenais/diagnóstico , Asfixia Neonatal/complicações , Veias Cerebrais , Hemorragia/diagnóstico , Humanos , Recém-Nascido , Trombose Intracraniana/diagnóstico , Angiografia por Ressonância Magnética , Masculino , Prognóstico , Trombose Venosa/etiologiaRESUMO
In patients with Mycoplasma pneumonia extrapulmonary manifestations such as encephalitis, meningitis, cerebellar and brain stem involvement, cranial nerve lesions, peripheral neuropathy, polymyositis have been observed. We report a 16-year-old girl with M. pneumonia infection, acute behavioral changes and coma. Treatment with high dose methyl-prednisolone and clarithromycin led to rapid clinical improvement.