RESUMO
Auto-brewery syndrome is defined as intestinal distillation syndrome and is probably caused by an overgrowth of microorganisms which metabolize carbohydrates to ethanol. In this report, we describe the case of a patient with classical symptoms of auto-brewery syndrome, with no prior alcohol ingestion and clinical improvement after medical treatment was instituted. It is a very rare case and, due to its inadequate description in the medical literature, we attempt to describe the essentials of the disease and the diagnostic challenge it represents. (Acta Med Colomb 2022; 48. DOI:https://doi.org/10.36104/amc.2023.2565).
RESUMO
Actualmente la epidemiología de la Tuberculosis está íntimamente ligada a la del VIH. El conocimiento de la prevalencia de la coinfección VIH-TBC es un indicador del grado de avance de estas 2 epidemias. En Colombia de acuerdo a diferentes estudios se encuentra entre el 3 y el 15%. El trabajo tuvo como objetivo determinar la prevalencia del VIH en personas diagnosticadas con tuberculosis pulmonar y extrapulmonar en el municipio de Pasto, en el período de septiembre de 2005 a septiembre de 2006; realizando un estudio descriptivo transversal con 47 pacientes quienes previa consejería aceptaron mediante consentimiento informado que se les practicara las pruebas diagnósticas para VIH arrojando los siguientes resultados: De los 55 pacientes con diagnóstico de TBC, 47 (85.5%) aceptaron las pruebas diagnósticas de VIH. Se confirmaron 3 pacientes con diagnóstico de VIH, lo cual representa el 6.38% de coinfección VIH-TBC. Los pacientes coinfectados (100%) pertenecen al sexo masculino, con edades entre 25 y 44 años. De los 3 pacientes 2 (66.6%) presentaban formas pulmonares y 1 (33.33%) extrapulmonar. La mortalidad fue del 33.3% superior a la mortalidad del 85% que se presentó en pacientes con diagnóstico de TBC exclusivamente. Se concluyó que de VIH en pacientes con TBC estudiados en la ciudad de Pasto en el período observado, fue del 6.38% encontrándose en valores intermedios de los observados en otros trabajos nacionales sobre coinfección VIH-TBC.
Nowadays, the epidemiología of the tuberculosis is intimately related to that of HIV. The knowledge of the prevalence of coinfection HIV - TBC is an indicator of the degree of advance of these two epidemics. In Colombia is between a 3% and 15% according to different studies. Objective: To determine the prevalence of the HIV in people diagnosed with pulmonary and extrapulmonary tuberculosis in the municipality of Pasto from September 2,005 to September 2.006. A cross-sectional descriptive study was made in the municipality of Pasto, Department of Nariño, Colombia with 47 patients, who were diagnosed with pulmonary tuberculosis and extrapulmonary in the period between September 2,005 and September 2,006. They previously accepted by means of informed consent that HIV tests were made to them. Results: In the period September 2,005 to September 2,006, 55 cases of Tuberculosis were diagnosed, including pulmonary and extrapulmonary forms. From these 55 patients, 47 (85,5%) accepted to take the HIV tests. 3 patients were positive in HIV according to the tests (ELISA) and confirming (Western Blot), which represents VIH-TBC in the 6,38%. The infected patients (100%) belonged to masculine sex, with ages between 25 and 44. From the 3 patients with VIH/TBC, 2 (66, 6%) of them presented pulmonary forms and 1 ((33, 3%) displayed extrapulmonary form. The mortality between the patients was of 33, 3%, which was superior to the mortality of the 8.5% that appeared exclusively in patients with TBC diagnosis. The prevalence of HIV in patients with TBC studied in the city of Pasto in the period of September 2,005 to September 2,006 was of 6,38%, being in intermediate values from the observed in other national studies of HIV/TBC made in other departments.