Alta prevalencia de enfermedad tiroidea subclínica en sujetos que concurren a control de salud / High prevalence of subclinical thyroidal disease among individuals attended in occupational health examinations

Background: There is no information about the prevalence of thyroidal diseases in the general Chilean population. Aim: To assess the prevalence of thyroidal diseases in individuals attended in occupational health examinations. Subjects and methods : Four hundred seventy two individuals were examined between 1998 and 1999. In all, serum levels of thyroid hormones, TSH and anti thyroidal antibodies (anti microsomal, anti thyroid peroxidase and anti thyroglobulin) were measured. Results: Forty four subjects were excluded from the study due to an incomplete medical record and 18 due to a personal history of thyroidal disease. Abnormal serum levels of thyroid hormones or TSH were detected in 28 subjects (6.8 percent). Four (1 percent) had hypothyroidism, 23 a subclinical hypothyroidism (5.6 percent) and one (0.2 percent) had hyperthyroidism. In 87 subjects (21.2 percent) at least one of the antibodies was positive. Positive anti thyroid antibodies were found in 14 of 28 subjects (50 percent) with abnormal thyroid hormone levels, compared with 73 of 382 subjects (19.1 percent) with normal thyroid hormone levels. Thyroid dysfunction was twice as frequent in women than in men. Conclusions: In this sample, a 6.8 percent prevalence of abnormal thyroid function tests was detected

Trastorno de pánico e hipertiroidismo: curso clínico en dos pacientes / Panic disorder and hyperthyroidism: report of 2 cases

In two females aged 27 and 32 years old, an aggravation of their panic disorder coincided with the appearance of clinical signs of hyperthyroidism. The clinical diagnosis was confirmed with the finding of raised thyroid hormone levels and undetectable TSH levels. These two cases highlight the importance of routine thyroid function assessment in patients with panic disorder, mainly in those with partial response to medications or when symptoms aggravate, despite an adequate treatment

Depresión post accidente vascular encefálico / Depression post vascular encephalic accident

El presente trabajo revisa la aparición de síntomas depresivos posterior a la ocurrencia de un accidente vascular encefálico. Se revisan las principales dificultades metodológicas para el estudio de la patología afectiva, la prevalencia. los rasgos clínicos, teorías etiopatogénicas, evolución y tratamiento del cuadro