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Indian J Lepr ; 1992 Oct-Dec; 64(4): 475-81
Artigo em Inglês | IMSEAR | ID: sea-54568

RESUMO

Dissemination of M. leprae to visceral organs is seen by four months onwards only in beige (C57BL/6/bgj) but not BALB/c mice following intravenous or intraperitoneal infections. Inoculation of the beige mouse derived M. leprae showed all the characteristics of M. leprae, including growth pattern in the foot-pads of BALB/c mice. M. leprae inoculated into foot-pads of beige mice multiplied faster than those in the foot-pads of BALB/c mice. The possibility of using beige mouse in chemotherapeutic studies in leprosy is discussed.


Assuntos
Animais , Modelos Animais de Doenças , Feminino , Hanseníase/microbiologia , Fígado/microbiologia , Camundongos , Camundongos Endogâmicos BALB C , Camundongos Endogâmicos C57BL/microbiologia , Mycobacterium leprae/crescimento & desenvolvimento , Baço/microbiologia
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