RESUMO
Objective To investigate the changes of lymphocyte subsets of 291 blood donors after dona-tion.Methods 291 cases of voluntary blood donors were enrolled in the study from January 2016 to December 2016.Before and 30 d after blood donation,cellular immune function and humoral immune function.The cellu-lar immune function and humoral immune function of 30 d before and after blood donation were compared,the changes of cellular immune function and humoral immune function before and after donation of 30 d between different genders.Results 30 d after blood donation,CD3+,CD4+lymphocytes and CD4+/CD8+were higher than those before blood donation(P<0.05).There was no significant difference in the levels of IgA,IgM and IgG before and after blood donation(P> 0.05).30 d after blood donation,CD3+,CD4+lymphocytes,and CD4+/CD8+were all higher than those before blood donation in both males and females(P<0.05);CD3+, CD4+lymphocytes,and CD4+/CD8+were detected before and after blood donation,between different genders there was no significant difference(P>0.05).There was no significant difference between males and females in IgA,IgM and IgG before and after blood donation(P>0.05).Conclusion There was no significant change in the humoral immune function in 291 cases of voluntary blood donors,but the proportion of T cell subsets increased.
RESUMO
Objective To investigate the effect of Yiqi Yangyin Huoxue Decoction combined with Western medicine therapy , while on this basis the observation group was combined with the on serum CRP ,TNF‐α,blood lipid and hemorheology levels in cor‐onary heart disease angina pectoris .Methods Totally 114 patients with coronary heart disease(CHD) angina pectoris were random‐ly divided into observation group (n=57) and control group (n=57) according to the random number table method .The control group was treated with Western medicine treatment ,while on this basis the observation group was combined with the therapy of Yiqi Yangyin Huoxue Decoction .The treatment cource was 4 weeks in the two groups .Serum CRP ,TNF‐α,blood lipids ,hemorheol‐ogy levels ,frequency and duration of angina pectoris attack ,efficacy of angina pectoris and ECG and adverse reactions were contras‐tively analyzed in the two groups .Results The levels of serum CRP and TNF‐αafter treatment in the two groups were decreased (P<0 .05);sthe serum levels of CRP and TNF‐α after treatment in the observation group were lower than those in the control group(P<0 .05);the TG ,TC and LDL‐C levels after treatment in the two groups were decreased (P<0 .05);the TC ,LDL‐C and TG levels after treatment in the observation group were lower than those in the control group (P<0 .05);fibrinogen ,plasma vis‐cosity and whole blood viscosityafter treatment in the two groups were decreased (P<0 .05);the fibrinogen ,plasma viscosity and whole blood viscosity after treatment in the observation group were lower than those in the control group (P<0 .05);the angina pectoris attack frequency after treatment in the two groups were reduced (P<0 .05) ,the duration was shortend (P<0 .05);but the angina pectoris attack frequency after treatment in the observation group was lower than that in the control group (P<0 .05) ,the duration was shorter than that in the control group (P<0 .05);the total effective rate of angina pectoris and ECG in the observa‐tion group was higher than that in the control group (P<0 .05) .The two groups had no serious adverse reactions during the treat‐ment process .Conclusion Yiqi Yangyin Huoxue Decoction combined with Western medicine can reduce serum CRP ,TNF‐α,blood lipid and hemorheologic levels in CHD angina pectoris ,and has remarkable curative effect with safety and reliability .