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J. appl. oral sci ; 17(spe): 13-18, 2009. tab
Artigo em Inglês | LILACS | ID: lil-576872

RESUMO

This study evaluated the occurrence of enteric bacteria and pseudomonads resistant to tetracycline and β-lactams in the oral cavity of patients exhibiting gingivitis (n=89), periodontitis (n=79), periodontally healthy (n=50) and wearing complete dentures (n=41). Microbial identification and presence of resistance markers associated with the production of β-lactamases and tetracycline resistance were performed by using biochemical tests and PCR. Susceptibility tests were carried out in 201 isolates of enteric cocci and rods. Resistance to ampicillin, amoxicillin/clavulanic acid, imipenem, meropenem and tetracycline was detected in 57.4 percent, 34.6 percent, 2.4 percent, 1.9 percent and 36.5 percent of the isolates, respectively. β-lactamase production was observed in 41.2 percent of tested microorganisms, while the most commonly found β-lactamase genetic determinant was gene blaTEM. Tetracycline resistance was disseminated and a wide scope of tet genes were detected in all studied microbial genus.


Assuntos
Adulto , Feminino , Humanos , Masculino , Enterobacteriaceae/efeitos dos fármacos , Boca/microbiologia , Pseudomonas/efeitos dos fármacos , Resistência a Tetraciclina/genética , Resistência beta-Lactâmica/genética , Antibacterianos/farmacologia , Biomarcadores , Prótese Total/microbiologia , Enterobacteriaceae/genética , Enterobacteriaceae/isolamento & purificação , Genes Bacterianos , Gengivite/microbiologia , Reação em Cadeia da Polimerase , Periodontite/microbiologia , Pseudomonas/genética , Pseudomonas/isolamento & purificação , Tetraciclina/farmacologia , beta-Lactamases/metabolismo , beta-Lactamases/farmacologia , beta-Lactamas/farmacologia
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