RESUMO
Background: The long QT syndrome (LQTS) is a disorder of myocardial repolarization characterized by a prolonged QT interval on the electrocardiogram (ECG). Hence the present study was aimed to determine prevalence of QT prolongation of the ECG and to assess its impact on outcomes in patients admitted in medical ICU of Noor Hospital of IIMSR Medical College, Badnapur, Jalna, Maharashtra, India.Methods: This prospective observational study was carried out during the period of October 2016 to March 2018, for assessment of prevalence of prolonged QTc at admission and its impact on outcomes in medical ICU. QTc calculated by bazett’s formula of >440 ms for males and >460 ms for females was considered as prolonged. Details of illness, clinical observations and laboratory parameters were also monitored.Results: The total 150 patients were studied and there was a high prevalence (32%) of prolonged QTc at admission to the ICU which reduced to 20.5% on day 3. Patients with prolonged QTc were found to be at high risk for adverse outcomes and their ICU and hospital stay was more.Conclusions: The study concluded that prolonged QTc is common in authors’ medical ICU at admission (32%). Patients with QTc prolongation were at higher risk for adverse outcomes and their ICU and hospital stay was more.
RESUMO
Background: The objective of the present research was to study clinical profile of rheumatic patients having infections including correlation of infection with different parameters and DMARDS and to study incidence pattern of various infections.Methods: All patients of various Rheumatic diseases with infections who fulfil inclusion criteria who were enrolled in this study. Duration of study was six months. A total of 300 patients where studied out of which 50 were cases and the rest were control.Results: Incidence of infection was high in extremes of age. Overall incidence of infection was slightly higher in females. Infection rate was 16.66%. Incidence of infection was highest among vasculitis group. Kidney was the most common organ involved. Incidence of infection was more in patients having anemia and leukopenia. Tuberculosis was the most common infection found in Rheumatic patients.Conclusions: Infection was more common at extremes of age and more common in females. SLE was most common disease encountered while kidney was most common organ to get involve in disease process. Patients with anemia and leukopenia had statistically significant incidence of infections. Tuberculosis is most common infection encountered in Indian rheumatic patients.