Impacto del tamaño de la cavidad en la resistencia de unión de sellantes resinosos. Estudio in vitro / Impacto do tamanho da cavidade na resistência de união de selantes resinosos. Estudo S. mutans / Impact of cavity size on bond strength of resin sealants - S. mutans study

Objetivo: Evaluar la resistencia de unión al desalojo de sellantes resinosos en cavidades en dentina de diámetros diferentes. Material y métodos: Se realizó un estudio S. mutans aleatorio, doble ciego, con 60 incisivos bovinos (n = 10 cuerpos de prueba por grupo) que recibieron un corte en sentido longitudinal, utilizando disco de corte diamantado de alta concentración doble cara, para obtención de una lámina de esmalte / dentina de 1 mm de espesor. A continuación, fueron confeccionadas restauraciones con dos diferentes sellantes resinosos - Fluroshield® (padrón oro) e Ionoseal® - en cavidades con diámetros de 3, 4 y 5 mm. Después de 2 meses de almacenamiento en Originalagua, los especímenes fueron sometidos a la prueba de resistencia de desalojo Resultados: Los sellantes evaluados presentaron valores de resistencia de unión similares (p = 0,357). De la misma forma, el diámetro de las cavidades no interfirió en los valores de resistencia de unión de los sellantes resinosos evaluados (p = 0,068). Conclusión: Podemos sugerir que es posible sellar lesiones cavitadas en la mitad externa de dentina con diámetros de 3, 4 y 5 mm con diferentes sellantes resinosos, ya que estos materiales presentaron resistencias similares cuando se aplican a la prueba desalojo.

Objetivo: Avaliar a resistência de união ao push out de selantes resinosos em cavidades em dentina de diâmetros diferentes. Materiais e métodos: Foi realizado um estudo S. mutans randomizado, duplo-cego, com 60 incisivos bovinos (n=10 corpos de prova por grupo) que receberam um corte no sentido longitudinal utilizando disco de corte diamantado de alta concentração, dupla face, para obtenção de uma fatia de esmalte/dentina com 1 mm de espessura. Foram confeccionadas então restaurações com dois diferentes selantes resinosos ­ Fluroshield® (padrão ouro) e Ionoseal® ­ em cavidades com diâmetros de 3, 4 e 5 mm. Após 2 meses de armazenamento em água, 2019os espécimes foram submetidos ao teste de resistência de push out. Resultados: Os selantes avaliados apresentaram valores de resistências de união semelhantes (p=0,357). Da mesma forma, o diâmetro das cavidades não interferiu nos valores de resistência de união dos selantes resinosos avaliados (p=0,068). Conclusão: Podemos sugerir que é possível selar lesões cavitadas em metade externa de dentina com diâmetros de 3, 4 e 5 mm com diferentes selantes resinosos, uma vez que os materiais apresentaram resistências similares quando aplicados ao teste push out.

Purpose: To evaluate the bonding strength to push out of resinous sealants in dentin cavities of different diameters. Materials and methods: A double-blind, randomized, in vitro study with 60 bovine incisors (n = 10 test specimens per group) was performed in a longitudinal direction using a high concentration, double-sided diamond cutting disc for obtaining a slice of enamel / dentin 1 mm thick. Restorations were then made with two different resin sealants - Fluroshield® (gold standard) and Ionoseal® - in wells with diameters of 3, 4 and 5 mm. After 2 months of storage in water, the specimens were submitted to the push-out resistance test. Results: The evaluated sealants showed similar bond strength values (p = 0.357). Likewise, the diameter of the wells did not interfere in the bond strength values of the resin sealants evaluated (p = 0.068). Conclusion: It is possible to seal cavitated lesions in Latinoamericanathe external half of dentin with diameters of 3, 4 and 5 mm with different resinous sealants, since the materials presented similar resistance when applied to the push out test.

Probiotic therapy reduces inflammation and improves intestinal morphology in rats with induced oral mucositis

Abstract The aim of the present study was to evaluate the effect of systemic administration of probiotics (PROB) on the progression of experimentally induced oral and intestinal mucositis in rats immunosuppressed by chemotherapy (5-fluorouracil: 5-FU). Twenty-four rats were divided into the following groups (n=6): GC (control), GPROB, G5FU and G5-FU/PROB. Groups GPROB and G5-FU/PROB received 1 g of probiotic incorporated into each 100 g of feed (Bacillus subtilis, Bifidobacterium bifidum, Enterococcus faecium and Lactobacilllus acidophilus), beginning 30 days before oral mucositis induction. Groups G5FU and G5-FU/PROB received 60 mg/kg of 5-FU on days 0 and 2. The left oral mucosa of each animal was irritated by mechanical trauma (days 1 and 2). On days 3 and 7, three animals from each group were sacrificed, and their oral mucosa and small intestine were biopsied and processed for histopathological analysis. Groups G5-FU and G5-FU/PROB showed ulcerated oral lesions at day 3, with progression in group G5-FU and regression in group G5-FU/PROB at day 7. Histologically, less severe signs of inflammation in the oral mucosa were observed in group G5-FU/PROB than in group G5-FU. Regarding the intestine, villus-related defects of lesser magnitude were observed in group G5-FU/PROB, compared with group G5-FU. Group GPROB showed greater villus height than group GC. It can be concluded that probiotic supplementation reduced oral and intestinal inflammation in immunosuppressed rats with experimentally induced mucositis, and may protect the intestine from changes induced by chemotherapy, thus contributing to overall health.