[Role of fibrin/fibrinogen degradation products in prognosis of patients with head trauma]

Accident is the third common cause of mortality in population .Traumatic head injury is the most common cause of mortality among these events. In different studies, coagulation disorder is one of the most important factors for determination of severity of injury. The present study was designed to evaluate post traumatic fibrinolysis in adults after head injury. In this descriptive cross sectional study, ninety six patients [22 patients with mild head injury and 74 patients with severe or moderate head injury], who admitted in Mashhad Shahid Kamyab Hospital for six months, were chosen randomly. All of them had only head injury and admitted in hospital in less than 6 hours after trauma. The clinical and paraclinical findings including FDP were evaluated. Data was gathered in a questionnaire and analyzed by descriptive statistics and frequency distributes tables. Most cases of delayed hematoma happened within 14 hours of trauma. FDP value was correlated with severity of head injury and there was a meaningful correlation between FDP value and GCS. Higher FDP was seen with lower BMR, and vise versa. The most common cases with delayed hematoma were intracerebral hematoma. FDP may be a valuable predictive factor in traumatic head injury and changes in coagulation cascade may improve the outcome of patients with traumatic head injury

Intraventricular hemorrhage in blunt head trauma

Before the CT scan was widely used for imaging, intraventricular hemorrhage [IVH] was a rare diagnosis and in most cases proved fatal. Currently, thanks to the CT scan IVH. is easily diagnosed. Prognosis of IVH is very poor and almost always is accompanied with other intracranial traumatic lesions and pure traumatic IVH is very rare. This descriptive study done on 28 patients with IVH. During a year 742 patients were admitted to the Neurosurgical Intensive Care Unit of Shahid Kamyab Hospital. In 28 cases the leading cause of admittance was motor vehicle accidents, Most of the patients were between the age of 21-30., Out of 28 cases had IVH, 5 patients [18%] had pure IVH and the remaining others had intera cranial legions like, parenchymal hemorrhage, sub-arachnoid hemorrhage, brain contusions, subdural hemorrhage and acute hydrocephalus in one patient [3.6%]. 82% of patients had a very low-conscious level at admittance, which measured by the Glasgow Coma Scale, lower than 8. Mortality was higher than 61%. Four patients had surgical treatment and all died. Eight cases did not have any surgical procedure. Traumatic IVH is very rare in severe blunt head injuries and is associated with other brain lesions and had a poor prognosis. Mortality rate is different and depends on other accompanying intracranial lesions. Surgical intervention does not have a significant effect for a successful out come