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1.
Medical Forum Monthly. 2014; 25 (1): 62-65
em Inglês | IMEMR | ID: emr-161267

RESUMO

Validity of pleural fluid protein in differentiating tuberculouse from malignant pleural effusion keeping histopathology as gold standard. Cross sectional study. This study was conducted in the Pulmonology department post graduate medical institute, Lady Reading Hospital Peshawar, Khyber Pakhtunkhwa [KPK] Pakistan from March 2009 to March 2010. One hundred and seventy nine patients having clinical suspicion of pulmonary tuberculouse and malignancy and fulfilling the inclusion criteria were subjected to Abrams needle biopsy, plural tissue was examined by histopathology. Biopsy in order to know the significant difference of pleural fluid protein level between tuberculous and malignant pleural effusion, histopathology finding and protein concentration were determined their frequency and percentage. Among total number of 179 patients one hundred and fourteen [63.69%] were male and sixty five [36.32%] were female. The age limit from 15-80 years, the result shows that 60.9% were tuberculous and 39.9% were malignant pleuraleffusion, among these malignant 20 [11.2%] showed primary and 50 [27.9%] secondary malignancy. Tuberculous PE was more common in younger age group while malignant PE in older age group, 32 number of patients falling in category A, 59 in category B, and 88 in category C.A protein level in belonging to category C, there was statistically significant difference between tuberculous and malignant PE, tuberculous PE have high concentration of protein than malignant PE, The category [A] have malignant PE. Plural fluid total protein level determination and differentiating is a valuable tool in reaching to the diagnosis of suspectedtuberculouse from malignant pleural effusion provided it is used in addition to the adequate clinical scenario

2.
Medical Forum Monthly. 2014; 25 (5): 66-69
em Inglês | IMEMR | ID: emr-147287

RESUMO

To determine the frequency of urinary symptoms in postmenopausal women with Uterovaginal Prolapse. Descriptive study. This study was conducted in Department of Obstetrics and Gynecology Unit II, Dow University of Health Sciences and Civil Hospital Karachi Pakistan from July 2006 to June 2007/ 60 [sixty] Consecutive pts were included in the study through structural Proforma from the outpatient, ward or emergency. Informed consent was obtained. A detailed history and related examinations and investigations were done. These include Urine DR, Urine C/S and Urodynamics like cystometry in selected patients. Majority of Women found have symptoms were at the age of 60 yr [36.66%] While urinary symptoms less seen at the age of 80 yr [6.66%] while Parity 6-10 was higher in Postmenopausal women to have urinary symptoms [63.33%]. The urinary symptoms found in Postmenopausal women were frequent urine passing [33.33%], Nocturia [83.33%], Retention of urine [20.0%], Dysuria [26.66%], Voiding difficulty [53.35%], Urge incontinence [20.0%] and Stress incontinence [53.33%]. Pelvic organ Prolapse and urinary symptoms like incontinence are prevalent in older women and are associated with age. Large studies are required to assess the relationship of urinary symptoms with Uterovaginal Prolapse. Because these urinary symptoms effect over quality of life of women so it is recommended to reduce genital prolapsed and associated urinary symptoms by implementing some measures such as health education of women and weight control

3.
Medical Forum Monthly. 2014; 25 (6): 50-53
em Inglês | IMEMR | ID: emr-153164

RESUMO

To compare the efficacy of H[1] blocker, H[2] blocker, corticosteroid in combination or individually in resolution of the sign and symptoms of acute urticaria. Randomized control trial. This study was carried out at Medical Department, Naseer Teaching Hospital, Peshawar, Khyber Pakhtunkhwa [KPK] for the period of six months [July 2012 through December 2012]. In this study 140 adult patients of both gender with acute urticaria were treated with either H[1] blocker [group A], H[2] blocker [group B] or in combinations of H[1] blocker + H[2] blocker [group C], H[1] blocker + H[2] blocker + dexamethasone [group D], H[1] blocker + dexamethasone [Group E], H[2] blocker + dexamethasone [Group F] or Dexamethasone [group G] alone. The end points were resolution of sign and symptoms in each group of patients [minimum 3 hours after treatment]. Pregnant females, anemic and Patients with cardiac disease were excluded. H[1]+ H[2] blockers + dexamethasone found to be most effective therapeutic combination [95% of patients] in resolution of sign and symptoms of acute urticaria, followed by H[1] blocker + dexamethasone [90%] and H[1]+ H[2] blockers [85%]. This study concludes that the combination of H[1]+H[2] blockers + dexamethasone is more effective in relieving the patient from the sign and symptom of acute urticaria as compared to H[1] blocker or H[2] blocker or dexamethasone given alone or in combination of any two

4.
Medical Forum Monthly. 2013; 24 (12): 86-88
em Inglês | IMEMR | ID: emr-152438

RESUMO

Lipid and lipoprotein is influenced by thyroid hormone. Global distribution thyroid disease is very common in Indo- Pak. Hypercholesterolemia is common finding in hypothyroid patients. This study was conducted to know the prevalence of thyroid dysfunction and its relationship with dyslipidemia. Cross Sectional Study. The study was conducted at the Department of Pathology Jinnah Medical College Warsak Road Peshawar for the period from December 2012 to May 2013. 300 patients suspicious of thyroid element were included in study group. 100 healthy control subjects with no history of any thyroid and other chronic illness were included in control group, serum FT4, TSH and total cholesterol was estimated by Elisa and colorimetric method respectively and Results were analyzed by applying "student T test" and Chi-square". Out of 300 sera tested 78 [260] had thyroid dysfunction Hypothyroid patients serum showed significantly raised cholesterol level, however no significant association between total cholesterol and raised thyroxin level observed. Hypercholesterolemia was noted significantly in hypothyroid patients indicating need for monitoring the cholesterol level in thyroid dysfunction to avoid the risk of development of cardiovascular disease

5.
Medical Forum Monthly. 2013; 24 (11): 91-93
em Inglês | IMEMR | ID: emr-161193

RESUMO

To evaluate the therapeutic efficacy of this most important nonsteroidal anti-inflammatory drug by using series of 60 patients with osteoarthritis. Cross sectional study. The prospecting study was undertaken from amongst patients visiting the outpatient orthopedic department of District Head Quarter Hospital Charsadda of Khyber Pakhtunkhwa [KPK] for the period of six months from 1[st] January 2011 to 30[th] June 2011. This study was conducted on a mixed population of patients presenting with symptomatic osteoarthritis, which is relatively a common disease. Studies have shown that, the age of 40, 0% of all persons developed from mild clinical symptoms to degenerative changes in their weight bearing joints. indicates a significant therapeutic efficacy as compared to placebo, both at the 2[nd] and 4[th] week of treatment, table 3 represent the comparison of Piroxicam with placebo in the reduction of mean walking pain [hip] 2[nd] and 4[th] week of treatment on the basis of four point scale. The present study revealed sustained and significant improvement in the osteoarthritis of the knee or hip joint with Piroxicam treatment resulting in marked reduction in night-pain mean walking pain, and improved objective assessment in the functions of affected joints as compared to the findings emerging out of the use of the naproxen, aspirin and placebo

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