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Biomedical and Environmental Sciences ; (12): 204-207, 2014.
Artigo em Inglês | WPRIM | ID: wpr-270614

RESUMO

This paper is aimed to study the effect of ADL on expression of β1-AR and M2-AchR in myocardial cells of rats exposed to microwave radiation. Immunohistochemistry, Western blot and image analysis were used to detect the expression of β1-AR and M2-AchR in myocardial cells at 7 and 14 d after microwave exposure. The results show that the expression level was higher in microwave exposure group and 0.75 g/(kg•d) ADL group than in sham operation group and significantly lower in 1.5 and 3.0 g/(kg•d) ADL groups than in microwave group. So we have a conclusion that the expression of β1-AR and M2-AchR is down-regulated in myocardial cells of rats exposed to microwave radiation. ADL can protect rats against microwave-induced heart tissue injury.


Assuntos
Animais , Masculino , Regulação para Baixo , Medicamentos de Ervas Chinesas , Farmacologia , Coração , Micro-Ondas , Miocárdio , Biologia Celular , Metabolismo , Substâncias Protetoras , Farmacologia , Ratos Wistar , Receptor Muscarínico M2 , Metabolismo , Receptores Adrenérgicos beta 1 , Metabolismo
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