RESUMO
RESUMEN Las taquicardias ventriculares de larga duración o incesantes pueden causar insuficiencia cardíaca, disfunción del ventrículo izquierdo y cardiomiopatía, cuadros que revierten una vez resueltas las arritmias. Se trata de un diagnóstico de exclusión: puede existir una cardiopatía de base que empeora con la taquicardia y debe precisarse si la arritmia lleva a la cardiomiopatía (puede existir un subregistro) o viceversa. Se presenta un paciente con taquicardia incesante del tracto de salida del ventrículo derecho, de larga evolución, con repercusión hemodinámica, cardiomiopatía dilatada y disfunción grave del ventrículo izquierdo, rebelde a fármacos antiarrítmicos y con dos ablaciones fallidas, pendiente de biopsia endomiocárdica y nueva ablación de su taquicardia. Se discuten algunas pistas para diferenciar las arritmias del tracto de salida del ventrículo derecho, en sus variantes benignas (las más frecuentes) y malignas. Algunas pistas para diferenciarlas son: la duración del complejo QRS, el intervalo de acoplamiento de la extrasístole y la frecuencia de la taquicardia.
ABSTRACT Long-lasting or incessant ventricular tachycardias may cause heart failure, left ventricular dysfunction, and cardiomyopathy; conditions that reverse once the arrhythmias have been solved. This is a diagnosis of exclusion: there may be a basic heart disease that worsens with the tachycardia and it must be clarified whether the arrhythmia leads to cardiomyopathy (there may be an underregistration) or vice versa. A patient with incessant right ventricular outflow tract tachycardia, with long evolution, hemodynamic repercussion, dilated cardiomyopathy and severe dysfunction of the left ventricle, refractory to antiarrhythmic drugs and with two failed ablations, pending endomyocardial biopsy and new ablation of his tachycardia is presented. Some clues to differentiate right ventricular outflow tract arrhythmias, in their benign (most frequent) and malignant variants, are discussed. Some clues to differentiate them are: the duration of the QRS complex, the coupling interval of premature contractions and the heart rate of the tachycardia.
Assuntos
Arritmias CardíacasRESUMO
El aceite de semillas de calabaza ha sido ampliamente utilizado en el tratamiento de la hiperplasia prostática. En el presente trabajo se estudió el efecto del extracto lipofílico de semillas de Cucurbita pepo L (ELMSC) en el modelo in vivo de hiperplasia prostática experimental inducida por propionato de testosterona durante 15 días. Se observó que el ELMSC a las dosis de 400 y 200 mg/ kg provocó una disminución significativa del crecimiento prostático. Nuestros resultados indican que el ELMSC a dosis mayores de 200 mg/ Kg inhibe el crecimiento prostático inducido por la testosterona en el modelo experimental de hiperplasia prostática en ratas.
Oil from pumpkin seeds has been widely used in the treatment of prostatic hyperplasia. In the present paper, the effect of lipophilic extract of Cucurbita pepo L seeds (ELMSC) was studied in an in vivo model of testosterone propionate -induced experimental prostatic hyperplasia during 15 days. It was found that ELMSC at doses of 400 and 200 mg/kg caused a significant decrease of prostatic growth. Our findings showed that doses of ELMSC over 200 mg/kg inhibits the testosterone-induced prostatic growth in the experimental model of prostatic hyperplasia in rats.
RESUMO
Even when there is not direct relation between psoriasis and AIDS, there have been reported impressive manifestations of psoriasis in AIDS diagnosis, difficulties in response to therapy, increase of serious forms of the disease, and clearing of lesions in terminal phase of AIDS. Two cases in which the two diseases are associated were presented. Both cases had outbreaking psoriasis guttata, one of them after being diagnosed with AIDS, in addition to have other dermatosis such as leukoplasia and ungual candidiasis; and the two patients also had scabies. Additionally, presentation of generalized lesions resistant to prescribed therapies was observed.