RESUMO
Background: Neonatal septicemia is the major cause of Neonatal mortality. It might be possible to reduce these deaths by early diagnosis and proper management. Objectives: (1) To find out various bacteriological agents involved in neonatal septicaemia in PDU Medical college & Hospital Rajkot (2) to findout the organisms responsible for early onset and late onset neonatal sepsis. Methods: A hospital based prospective study was carried out in 100 clinically supsected cases of neonatal septisemia in New Born Intensive Care Unit (NICU) at P.D.U Medical College & Hospital Rajkot. Results: Out of 100 neonates with clinically suspected neonatal septicemia, 62(62%) were blood culture positive. Gram negative bacteria accounted for 50(80.65%) & Gram positive bacteria accounted for 12(19.35%) of all cases. Among Gram Negative bacteria Klebsiella spp 25(40.32%) being the most common organism & Staphylococcus aureus 8(12.90%) being the most common organism among Gram Positive bacteria. Late sepsis was most commonly associated with klebsiella spp19 (41.3%).Conclusion: Neonatal septicaemia should be diagnosed urgently to reduce the mortality. Suspected infection based on clinical criteria need to supported by microbial investigation to find causative organisms and their antibiotic sensitivity pattern.