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Background: Cancer related anemia (CRA) is a major healthcare issue among patients suffering with cancer. In the Indian context, these figures are likely to be higher due to the prevailing malnutrition and low socio-economic status in the general population. This observational hospital-based study has been conducted among cancer patients with following objectives to assess the socio demographic profile of different cancer patients admitted at hospital. To measure hemoglobin level among different cancer patients admitted at hospital on the basis of socio demographic profile and type of cancer.Methods: The registers maintained in the department of Radiotherapy were checked and those belonging to the year 2011-12 were used to process and analyse the cancer patient抯 data in respect to age, type of cancer, hemoglobin level admitted in health care facility.Results: By far distribution of Hb level is concerned among all cancer patients, 87.56% patients were having Hb level more than 9 gm% and around 12.43 % patients were having Hb level less than 9 gm%. Majority of patients whose Hb level was less than 9gm% were belonging to age group more than 45 years.Conclusions: It is very much evident that anemia among cancer patients is a major healthcare problem and surely adds into morbidity and mortality of cancer patients. It may further aggravate the health condition of cancer patients if not corrected timely. Therefore, anemia among cancer patients should be taken and treated very seriously.
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Background: Obesity is a complex disorder that involves some degree of over-consumption1 coupled with a metabolic derangement. As ADA has been putatively associated with inflammation, and adipose tissue inflammation is the hallmark of insulin resistance in obese T2DM patients. This study attempted to compare serum ADA in T2DM subjects.Methods: This observational cross-sectional study was conducted in the Department of Biochemistry at MGM Medical College and MY Hospital. All the patients and controls were clinically examined, and routine biochemical tests were analyzed for all subjects. ANOVA has been applied to assess the variance between groups.Results: Mean age of controls was 56.91 years where as mean age in the group of a subject with Obesity with diabetes was 40.91 years and with Obesity without diabetes was 48.10 years. ADA level was more among diabetes patients having obesity than diabetes patients having no obesity and controls.Conclusions: This is very much evident through this study that ADA may be treated as prognostic predictor of diabetes either linked to obesity or not, though more studies are warranted in same direction to make this finding conclusive and acceptable biochemical evidence.
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On account of improved life expectancy, better education and health facilities in India, the proportion of the geriatric population has gone up. In India, prevalence of depression estimated to be 4.5% in the year 2015, which affects about 57 million people. Objective: To determine the prevalence of depression and its epidemiological correlates among geriatric people residing in southern Haryana, India. Material and Methods: This community based study with cross-sectional design was conducted in rural and urban field practice areas of department of Community Medicine. Geriatric people were contacted by investigators through house to house visit. Study subjects were screened for depression by using standard shorter version Geriatric Depression Scale (GDS-15). Pearson’s Chi-square test was used for categorical variables. Stepwise multiple logistic regression was used to find out an independent factors associated with depression. Result: A total of 308 elderly persons belonging to rural and urban areas participated in our study. Prevalence of depression (GDS score >5) among the elderly population in the present study was found to be 22.72% (95% CI: 18.2-27.8). Conclusion: Present study depicted that every fourth elderly person was suffering with depression. Nuclear family, sleep problems, not consulting elderly in decisions, chronic morbidity, lack of physical activities, and death of close relatives were identified as risk factors of depression.
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Background: Evaluation of jaundice patients should include proper history and examination, laboratory investigation and imaging investigations (non invasive like Ultrasound (U\S), CT and MRI or invasive like ERCP and PTC). Aim of Study: The aim of this prospective study is to evaluate the diagnostic reliability of U\S and MRI-MRCP in patients of obstructive jaundice in clinical practice. Materials and Methods: This is a prospective study performed on 60 patients (31 male and 29 female) with an average age of 55.53 +/- 17.57 years presented with obstructive jaundice for whom abdominal ultrasound (U\S) and magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography (MRCP) on 3 Tesla was performed in the departments of radiology in Max super speciality teaching hospital, saket, Delhi, India from May 2012 to May 2013. The final diagnosis was achieved by endoscopic retrograde cholangiopancreatography (ERCP) and \or surgery and confirmed by histopathology. Results: The most common cause of obstructive jaundice in our study was common bile duct stones (51.65%) followed by tumors (33.3%) then benign strictures (10.0%), choledochal cyst (3.33%). In this study, MRI-MRCP could differentiate surgical from medical jaundice in all cases, while U\S could differentiate surgical from medical jaundice in 91.25% of cases. MRI-MRCP correctly defines the level of obstruction in all cases (100%). While U\S correctly define the level of obstruction in only 78% of the total cases. MRI-MRCP correctly suggests the most possible cause of obstruction in 96.25% of cases. While USG is correctly suggests the most possible cause in only 76.3%. Conclusion: So that USG as a screening modality is useful to confirm or exclude biliary dilatation & to choose patients for MRCP examination. MRI-MRCP is a useful non-invasive and essential method in the preoperative evaluation of patients with obstructive jaundice. In addition MRI-MRCP was superior to U\S or ERCP in studying the extent & staging of malignant lesions.
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Background: In children under 3 years old, fever is a common presenting symptom to the physician. Fever may be an indication of a mild infectious process such as a viral upper respiratory infection or a more serious infectious process such as bacteremia, bone and joint infections, urinary tract infection, pneumonia, soft tissue infection, bacterial enteritis, meningitis, sepsis and possibly death. The evaluation of fever in this age group has great clinical importance, as any of the serious bacterial infections whose presence it may signal may have grave morbidity if not treated. However, there exists scanty data on risk of bacteraemia among febrile children of developing countries and what clinical predictors, if any, could identify those febrile infants with bacteraemia. Present study aims to determine the prevalence of bacteremia in febrile children and the effect of low birth weight, poor feeding practices & coverage of vaccination and malnutrition which are more prevalent in developing countries like india. Objective: 1. To assess prevalence of bacteremia among hospitalized febrile children aged 3 months to 36 month. 2. To study effect of birth weight, feeding practices, vaccination and malnutrition on bacteremia in febrile children. 3. To find out different bacterial isolates. Methods: 84 consecutive febrile children attending children emergency ward of Kamla Nehru Hospital, Bhopal, aged 3 months to 36 months with rectal temperature 38 C( 100.4F) with negative H/o of antimicrobial use and who requiring hospitalization were included in the study. Exclusion criteria were current use of antimicrobial use. Children meeting eligibility criteria were studied to identify clinical predictors of bacteremia. Study subjects underwent full clinical evaluation and had blood culture done for aerobic organisms by standard method. Variable examined were age, sex, temperature, birth weight, vaccination, feeding practices, physical indices & blood culture results. Results: 50%(42) subjects were bacteremic. Klebsiella (38%), Staph aureous (28.5%) and E. coli (23.80%) of positive cultures were commonly associated.9 variables were found to be significant independent predictor of bacteremia. These were duration of fever >3 days (p=.015), birth weight <2.5 kg, no vaccination (p=.000458), low weight for age (p=.022), stunting (p=.014), presence of edema (p=.04). Conclusion: above mentioned factors are associated with increased risk of bacteremia in febrile children. Prevention of these factors can greatly reduce the chances of bacteremia in febrile children. Clinician practicing in such a setting needs to be aware of the increased risk of bacteremia in children with these clinical features.
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Introduction: Injury is a major, preventable public health problem in terms of morbidity, premature mortality or disability. This study aims to assess the epidemiology of injury in patients admitted to a tertiary care centre in northern India. Materials and Methods: Observational, Descriptive, secondary data based study of injury patients admitted in surgical emergency department of Government Medical College Hospital Chandigarh from July 2009 to June 2010. Results: Out of these total 7222 patients, 4129(57.2%) were of Road Traffic Accident (RTA) and 22.8% were of Assault. Male were at high risk of RTA. Although, overall males were at higher risk of assault but middle aged women were at higher risk than their counterparts. For ‘fall ‘females were at high risk. Assault cases were more prevalent during summer, while RTA cases were more prevalent during winter season and fall during rainy season were reportedly more. Majority (33.0%) of RTA injury was in the age group of 20-39 years (most productive age) and in the age group of <10 years falls were most common (56.0% of all injury).