RESUMO
In current scenario herbal formulations containing natural ingredients is more acceptable in public belief than chemical based synthetic formulations due to their safety and efficacy in reducing dental caries, pyorrhoea and preventing other dental and oral issues to which this generation is prone to. Clinically more effective and tolerable treatments should improve patient compliance with oral hygiene practices, further supporting medical professionals' efforts to avoid disease. Controlling the creation of dental plaque is the most efficient method of preventing the onset of dental disease. Microbes have an impact on its formation. Ayurveda recommends some daily use therapeutic procedures for the prevention and maintenance of oral health. These include: Pratisarana (gentle massage over tissue), Dant Dhavani (brushing), Jivha Lekhana (tongue scrapping) and Gandoosha (gargling) or oil pulling. The present study focused on preparation and validation of the classical formulation Trivargtrityadi yoga (TT yoga) which mentioned in Ashtang Sangraha by Acharya Vagbhata described in Dantadhawanacharya. It Contains Triphala, Trikatu, Trijatak and Kuth. These extracts have a variety of beneficial characteristics, including those that are anti-cancer, anti-fungal, and anti-ulcer, anti-caries, anti-bacterial and wound healing. The preparation of the formulation in accordance with traditional references and evaluation of its analytic and antibacterial properties are the objectives of this study.
RESUMO
Bhaishajya Kalpana- the pharmaceutical science of Ayurveda mainly deals with the planning and preparation of medicines. As per Ayurveda, an ideal drug is that one which can process into different forms. Though Ayurveda claims that no material is incapable of being utilized as medicine, none of them can be employed in the form in which they are available because they are not appetizing or easily absorbed by the human system. In this modern era, society prefers medicines which are more palatable, available, less dose and with more shelf life. In this view, as per the need of time, there is a need to modify the classical formulations in order to improve its characters and to make more acceptable. In this present study, Tiladi churna, a pure herbal formulation having minimum ingredients and its granules were prepared in departmental pharmacy. Churna Kalpana is considered as an Upakalpana of Kalka Kalpana which is one among the basic Panchavidha Kashaya Kalpana mentioned in classical texts while Khanda Kalpana or granules are the preparations added after 20th century which have more palatability and acceptance. Here both Tiladi Churna and granules were then compared to determine the efficiency in terms of method, duration of preparation and also in terms of organoleptic and physical parameters
RESUMO
Glucose-6-phosphate dehydrogenase (G6PD) defi ciency is the most common erythrocyte enzymopathy, being present in more than 400 million people worldwide that may lead to neonatal jaundice or hemolytic crisis due to drugs or infections. In our study, we aimed to study the frequency of G6PD defi ciency in neonates and the proportion of defi cient neonates, who developed neonatal hyperbilirubinemia in the study population. The study was an observational one, conducted at the Division of Genetics of Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, over a 2-year period from January 2011 to December 2012. A total of 6,000 newborns delivered during that period underwent newborn screening on 24-72 h of birth. Neonatal hyperbilirubinemia was presented in 13.3% of the study population. Of female neonates, 16% demonstrated G6PD defi ciency. This is worth noting for an X-linked recessive trait. Thus, in view of a high gene frequency for a disorder that is manageable with just elimination of few drugs and foodstuff, we stress the need for a newborn screening program for G6PD deficiency.