1.
Rev. Hosp. Clin. Univ. Chile
;
15(2): 154-158, 2004.
Artigo
em Espanhol
| LILACS
| ID: lil-476848
2.
Acta physiol. pharmacol. ther. latinoam
;
46(1): 49-56, 1996. ilus, tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-168106
RESUMO
A method was devised to determine the nature of the mechanism of the increase in renal (NA++K+)-ATPase in rats fed dilute ethanol for ten weeks. Antiserum to (NA++K+)-ATPase obtained from rabbits was added to microssomal fractions of Kidney and the activities of (NA++K+)-ATPase and Mg2+ ATPase were determined. The addition of antiserum resulted in a same pattern of dose-related inhibition of (NA++K+)-ATPase activity in control and ethanol-fed rats, whereas mg2+-ATPase was not affected by the antiserum. These results suggest that the mechanism of ethanol-induced enhancement of renal (NA++K+)-ATPase activity could be explained through an increase in the number of catalytic units.