Hipertension arterial y menopausia: epidemiología, mecanismos fisiopatológicos y tratamiento / Hypertension and menopause: epidemiology, physiopathology and treatment

Las enfermedades cardiovasculares constituyen la primera causa de muerte en las mujeres mayores de 50 años, edad en que se inicia el periodo de la menopausia. A pesar de la controversia existente del aumento de la prevalencia de hipertensión en mujeres post menopausia, existe evidencia de que en este estadio de la mujer se genera un ambiente pro hipertensivo. La hipertensión es considerada como uno de los principales factores de riesgos cardiovasculares. Aunque la hipertensión arterial es un problema médico mayor; su diagnóstico oportuno y tratamiento eficaz se alcanza en la minoría de las mujeres. Es necesario un tratamiento integral de los diferentes factores de riesgo cardiovasculares para lograr disminuir la mortalidad en este grupo de pacientes.

Cardiovascular diseases are the first cause of dead in women older than 50 years, age where menopause period begins Although the in crease of hypertension in postmenopausal women is controversial, there exists strong evidence that this state generate a pro hypertensive environment is considered one of the main cardiovascular risk factors. Although high blood pressure is a major medical problem the minority of women have a proper diagnose and effective, treatment. It is necessary an integral treatment of the different cardiovascular risk factors to diminish the mortality of this group of patients.

Cirugía transesfenoidal en enfermedad de Cushing durante gestación: Report of one case / Cushing's disease treatment with transsphenoidal surgery during pregnancy

We report a 26 years old female with Cushing's disease who became pregnant during the course of her disease. She was treated by transsphenoidal surgery during the second trimester of pregnancy, achieving resolution of hypercortisolism. She had a normal delivery at term, her offspring was healthy, and she had a normal lactation. Currently, five years after surgery, she is asymptomatic. According to our literature review, this patient is the fifth reported case of pituitary adenomectomy during gestation (Rev Méd Chile 2004; 132: 75-80).