Treatment of Membranous Glomerulonephritis with Cyclosporine A / 대한신장학회잡지

We investigated the relationship between hepatitis B and membranous glomerulonephritis and progress of disease after treatment with cyclosporine A. Twenty seven patients were reviewed retrospectively about clinical manifestations, laboratory findings, pathologic findings and progress of disease after treatment with steroid alone or steroid plus cyclosporine A. The male to female ratio was 3.5:1 and mean age was 8.9 years ranged from 2.8 to 16.9 years. The common clinical manifestations were edema(81%), asymptomatic proteinuria(19%) and micro- or macroscopic hematuria(78%). In viral marker studies, seventeen patients(63%) showed positive HBsAg and among them, 16 patients(59%) showed positive HBeAg. Eleven patients treated with steroid and cyclosporine A showed complete remissions and 12 cases among 16 patients treated with steroid alone showed complete remissions. In conclusion, sixty three percents of children with membranous glomerulonephritis have strong association with HBsAg. The most common clinical manifestation was edema. Patients treated with cyclosporine A and steroid showed better results than patients treated with steroid alone(P=0.03).

Minimal Change Nephrotic Syndrome Presented with Acute Renal Failure in a Child

Hepatoblastoma (HB) is a rare embryonic malignant tumor of the liver. Most morphological studies on HB have limited to the histological characteristics and only 3 cases of HB have been described in the cytology literature. We present 2 cases of HB occurring in children aged 1 year and 3 years, respectively. The distinctive cytologic features of fine needle aspiration of HB were clusters of tumor cells showing acinar and trabecular pattern, smaller tumor cells with a high nuclear-cytopalsmic ratio and hyperchromatic nuclei having prominent nucleoli, and the presence of extramedullary hematopoiesis and osteoid material. These features were also found in the cell block and the biopsy specimen, and appeared very useful in the differentiation of HB from hepatocellular carcinoma.

Unilateral Absence of Pulmonary Artery

Unilateral absence of pulmonary artery(UAPA) is a rare disease. We experienced 2 cases of UAPA in 5 month-old male patient and 16 year-old female patient with the chief complaint of dyspnea. Lung perfusion scan, cardiac catheterization with pulmonary and aortic angiography confirmed the diagnosis of UAPA.

Unilateral Absence of Pulmonary Artery

Unilateral absence of pulmonary artery(UAPA) is a rare disease. We experienced 2 cases of UAPA in 5 month-old male patient and 16 year-old female patient with the chief complaint of dyspnea. Lung perfusion scan, cardiac catheterization with pulmonary and aortic angiography confirmed the diagnosis of UAPA.